C4403

Calcium Ionophore A23187 mixed calcium magnesium salt

Approximate 1:15 molar ratio Ca:Mg.

• Synonym(s): Calcimycin, Calcium Ionophore mixed calcium magnesium salt
• Empirical Formula (Hill Notation): C₂₉H₃₇N₃O₆
• Molecular Weight: 523.62
• NACRES: NA.77
• PubChem Substance ID: 24892691
• UNSPSC Code: 12352202
• MDL number: MFCD00213962

Properties

• Quality Segment: 200
• form: solid
• storage temp.: 2-8°C
• SMILES string: [Mg++].[Ca++].CNc1ccc2oc(CC3OC4(CCC3C)OC(C(C)CC4C)C(C)C(=O)c5ccc[nH]5)nc2c1C(O)=O
• InChI: 1S/C29H37N3O6.Ca.Mg/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;;/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);;/q;2*+2
• InChI key: HKVXGTQLKZNXPV-UHFFFAOYSA-N

Description

Application

Ionophore highly selective for Ca²⁺. Potentiates responses to NMDA but not to quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

Other Notes

Ca and Mg contents may vary; actual content given on label.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable