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Z2251

Sigma-Aldrich

Zinquin ethyl ester

≥95% purity (HPLC), solid

Synonym(s):

2-Methyl-8-[(4-methylphenyl)sulfonylamino]-6-(ethyloxycarbonylmethyloxy)quinoline

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About This Item

Empirical Formula (Hill Notation):
C21H22N2O5S
Molecular Weight:
414.47
MDL number:
MFCD00797629
UNSPSC Code:
12171500
PubChem Substance ID:
329831605
NACRES:
NA.47

product name

Zinquin ethyl ester, ≥95% (HPLC), solid

Assay

≥95% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble
methanol: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c3nc(C)ccc3c1

InChI

1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3

InChI key

KCASTCXJTDRDFT-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

Used to detect zinc in cells by UV fluorescence.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV0053
MKCS7330
MKCP9144
MKCM8643
MKCM1106

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Yu Gong et al.
Journal of applied toxicology : JAT, 37(8), 895-901 (2016-11-20)
Recent studies showed that ZnO nanoparticles (NPs) might induce the toxicity to human endothelial cells. However, little is known about the interaction between ZnO NPs and circulatory components, which is likely to occur when NPs enter the blood. In this
Abrogation of Nuclear Factor-?B Activation Is Involved in Zinc Inhibition of Lipopolysaccharide-Induced Tumor Necrosis Factor-a Production and Liver Injury
Zhanxiang Z
The American Journal of Pathology (2004)
Travis J Bourret et al.
Molecular microbiology, 81(1), 259-273 (2011-05-14)
Borrelia burgdorferi encounters potentially harmful reactive nitrogen species (RNS) throughout its infective cycle. In this study, diethylamine NONOate (DEA/NO) was used to characterize the lethal effects of RNS on B. burgdorferi. RNS produce a variety of DNA lesions in a
Correlation of apoptosis with change in intracellular labile Zn(ll) using
Zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid],
a new specific fluorescent probe for Zn(ll)
Peter D
The Biochemical Journal (1993)
Phuong Kim To et al.
International journal of molecular sciences, 19(10) (2018-10-10)
The prostate gland contains a high level of intracellular zinc, which is dramatically diminished during prostate cancer (PCa) development. Owing to the unclear role of zinc in this process, therapeutic applications using zinc are limited. This study aimed to clarify
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