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M1824990

Metoclopramide

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

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About This Item

Empirical Formula (Hill Notation):
C14H22ClN3O2
CAS Number:
364-62-5
Molecular Weight:
299.80
Beilstein:
1884366
MDL number:
MFCD00211338
UNSPSC Code:
41116107
PubChem Substance ID:
329817892
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

metoclopramide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI

1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

InChI key

TTWJBBZEZQICBI-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813) , HTR3A(3359) , HTR4(3360)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metoclopramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

PHR1132

Metoclopramide Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

1440808

Metoclopramide hydrochloride, United States Pharmacopeia (USP) Reference Standard

M1825010

Metoclopramide impurity E, European Pharmacopoeia (EP) Reference Standard

M1825000

Metoclopramide hydrochloride, European Pharmacopoeia (EP) Reference Standard

M1824995

Metoclopramide impurity A, European Pharmacopoeia (EP) Reference Standard

1440820

Metoclopramide Related Compound B, United States Pharmacopeia (USP) Reference Standard

1440841

Metoclopramide Related Compound D, United States Pharmacopeia (USP) Reference Standard

1440819

Metoclopramide Related Compound A, United States Pharmacopeia (USP) Reference Standard

BP357

Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard

PHR2283

Metoclopramide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2284

Metoclopramide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2285

Metoclopramide Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2286

Metoclopramide Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2287

Methyl 4-(Acetylamino)-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2506

Metoclopramide Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2507

Metoclopramide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2508

Methyl 4-Amino-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

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Terri D Azzopardi et al.
The Annals of pharmacotherapy, 42(3), 397-402 (2008-02-21)
To compare the combination of oral metoclopramide plus an analgesic with oral triptan monotherapy in the treatment of migraine attacks in outpatients. A search of PubMed (1966-October 2007), EMBASE (1974-October 2007), and International Pharmaceutical Abstracts (1970-October 2007) was conducted using
Si-Jia Wu et al.
Hepato-gastroenterology, 59(119), 2064-2074 (2012-01-28)
The incidence of postoperative nausea and vomiting is truly high after laparoscopic cholecystectomy. Ondansetron and metoclopramide may be effective in preventing it. Our aim was to estimate the efficacy of ondansetron vs. metoclopramide in preventing postoperative nausea and vomiting after
Emergency medicine journal : EMJ, 30(7), 595-596 (2013-06-15)
A short-cut review was carried out to determine whether metoclopramide or prochlorperazine was better at relieving headache in patients attending the emergency department with acute migraine. Eighty-one papers were found using the reported searches, of which three presented the best
Paul F Lata et al.
The Annals of pharmacotherapy, 37(1), 122-126 (2002-12-31)
To review the safety and efficacy of chronic metoclopramide for diabetic gastroparesis. Medical literature was accessed through MEDLINE (1965 to October 2002) and PubMed (1965 to October 2002). Key search terms included metoclopramide; diabetic gastroparesis; and dyskinesia, drug induced. Metoclopramide
P Jay Pasricha et al.
Nature clinical practice. Gastroenterology & hepatology, 3(3), 138-148 (2006-03-03)
Metoclopramide, the only drug approved by the FDA for treatment of diabetic gastroparesis, but used off-label for a variety of other gastrointestinal indications, has many potentially troublesome adverse neurologic effects, particularly movement disorders. In this article, we comprehensively review the
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