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Key Documents

MAB303

Sigma-Aldrich

Anti-Acetylcholinesterase Antibody, clone AE-1

clone AE-1, Chemicon®, from mouse

Synonym(s):

Anti-ACEE, Anti-N-ACHE, Anti-YT

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

AE-1, monoclonal

species reactivity

canine, bovine, human, chicken, guinea pig, monkey

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ACHE(43)

Specificity

Acetylcholinesterase from human and monkey.

Immunogen

Acetylcholinesterase AChE from human erythrocyte.

Application

ELISA

Immunohistochemistry

Western Blot

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers
This Anti-Acetylcholinesterase Antibody, clone AE-1 is validated for use in ELISA, IH, IP for the detection of Acetylcholinesterase.

Physical form

Format: Purified
Liquid in 0.02M PB, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Pamela Jarrett et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 45(2), 150-157 (2018-03-07)
Neuronal ceroid-lipofuscinoses are a heterogeneous group of inherited disorders in which abnormal lipopigments form lysosomal inclusion bodies in neurons. Kufs disease is rare, and clinical symptoms include seizures, progressive cognitive impairment, and myoclonus. Most cases of Kufs disease are autosomal
Franziska Richter et al.
EBioMedicine, 41, 649-658 (2019-03-02)
The most prevalent inherited form of generalized dystonia is caused by a mutation in torsinA (DYT1, ∆GAG) with incomplete penetrance. Rodent models with mutated torsinA do not develop dystonic symptoms, but previous ex vivo studies indicated abnormal excitation of cholinergic
Sin Yeang Teow et al.
BMC biotechnology, 13, 107-107 (2013-12-07)
HIV genome is packaged and organized in a conical capsid, which is made up of ~1,500 copies of the viral capsid protein p24 (CA). Being a primary structural component and due to its critical roles in both late and early
Alicia J Dafferner et al.
Chemical research in toxicology, 30(10), 1897-1910 (2017-09-12)
Nerve agents and organophosphorus pesticides make a covalent bond with the active site serine of acetylcholinesterase (AChE), resulting in inhibition of AChE activity and toxic symptoms. AChE in red blood cells (RBCs) serves as a surrogate for AChE in the
Axodendritic contacts onto calcium/calmodulin-dependent protein kinase type II-expressing neurons in the barn owl auditory space map.
Rodriguez-Contreras, A; Liu, XB; DeBello, WM
The Journal of Neuroscience null

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