AB15554
Anti-AT2 Receptor Antibody
Chemicon®, from rabbit
Synonym(s):
Angiotensin II receptory type 2, AGTR2
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, rat
should not react with
human
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... AGTR2(186)
Specificity
Recognizes AT2 Receptor (Angiotensin II receptory type 2, AGTR2).
Immunogen
Purified peptide from the N-terminus of rat AT2 Receptor (Accession number P35351).
Application
This Anti-AT2 Receptor Antibody is validated for use in WB for the detection of AT2 Receptor.
Western blot: 1:200-1:500 using ECL on rat brain and mouse MS1 cell lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 3
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Marina C Muñoz et al.
The Journal of endocrinology, 221(2), 215-227 (2014-04-24)
The renin-angiotensin system (RAS) plays a crucial role in the regulation of physiological homeostasis and diseases such as hypertension, coronary artery disease, and chronic renal failure. In this cascade, the angiotensin-converting enzyme (ACE)/angiotensin II (Ang II)/AT1 receptor axis induces pathological
Brandon A Kemp et al.
Circulation research, 130(1), 96-111 (2021-11-20)
How signals from activated angiotensin type-2 receptors (AT2R) mediate inhibition of sodium ion (Na+) reabsorption in renal proximal tubule cells is currently unknown. Protein phosphatases including PP2A (protein phosphatase 2A) have been implicated in AT2R signaling in tissues other than
Roman Hafko et al.
PloS one, 8(7), e69234-e69234 (2013-07-11)
Commercially available angiotensin II At₂ receptor antibodies are widely employed for receptor localization and quantification, but they have not been adequately validated. In this study, we characterized three commercially available At₂ receptor antibodies: 2818-1 from Epitomics, sc-9040 from Santa Cruz
Renal functional effects of the highly selective AT2R agonist, β-Pro7 Ang III, in normotensive rats.
Lucinda M Hilliard Krause et al.
Clinical science (London, England : 1979), 134(7), 871-884 (2020-03-24)
Recently, we designed a group of peptides by sequential substitution of the naturally occurring α-amino acid throughout the Ang III peptide sequence with the corresponding β-amino acid. β-Amino acid substitution at the proline residue of Ang III (β-Pro7-Ang III) resulted
Francine Duchatsch et al.
Journal of the American Society of Hypertension : JASH, 12(8), 605-613 (2018-06-28)
Hypertension is one of the chronic side effects of dexamethasone (DEX) treatment; however, almost nothing is known about its acute effects. Therefore, the aim of this study was to investigate the possible mechanisms involved in blood pressure control after acute
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