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578576

Sigma-Aldrich

1,2-Epoxy-3-phenoxypropane

technical grade

Synonym(s):

2,3-Epoxypropyl phenyl ether, Glycidyl phenyl ether, Phenyl glycidyl ether

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About This Item

Empirical Formula (Hill Notation):
C9H10O2
CAS Number:
122-60-1
Molecular Weight:
150.17
Beilstein:
2744
EC Number:
204-557-2
MDL number:
MFCD00005133
UNSPSC Code:
12162002
PubChem Substance ID:
24880937
NACRES:
NA.23

grade

technical grade

vapor density

5.2 (vs air)

vapor pressure

0.03 mmHg ( 20 °C)

refractive index

n20/D 1.53 (lit.)
n20/D 1.530 (lit.)

bp

245 °C (lit.)

mp

3.5 °C (lit.)

density

1.109 g/mL at 25 °C (lit.)

SMILES string

C1OC1COc2ccccc2

InChI

1S/C9H10O2/c1-2-4-8(5-3-1)10-6-9-7-11-9/h1-5,9H,6-7H2

InChI key

FQYUMYWMJTYZTK-UHFFFAOYSA-N

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Related Categories

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Carc. 1B - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

237.2 °F - closed cup

Flash Point(C)

114 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
04726HA

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D L Deforce et al.
Carcinogenesis, 19(6), 1077-1086 (1998-07-17)
Calf thymus DNA was reacted in vitro with phenyl glycidyl ether (PGE) and was hydrolysed enzymatically, to the 5'-monophosphate nucleotides using deoxyribonuclease I (DNA-ase I) and nuclease P1. The adducts were concentrated using solid phase extraction (SPE), on a polystyrene
E Van den Eeckhout et al.
Journal of chromatography, 504(1), 113-128 (1990-03-30)
Thymidine and 2'-deoxyadenosine were reacted with phenyl glycidyl ether in order to study the formation of the corresponding 2'-deoxynucleoside adducts. Separation methods were elaborated using either reversed-phase high-performance liquid chromatography with photodiode-array detection, or centrifugal circular thin-layer chromatography. The adducts
Ida B Niklasson et al.
Chemical research in toxicology, 24(4), 542-548 (2011-03-05)
Epoxy resins are among the most common causes of occupational contact dermatitis. They are normally used in so-called epoxy resin systems (ERS). These commercial products are combinations of epoxy resins, curing agents, modifiers, and reactive diluents. The most frequently used
The inhalation toxicity of phenylglycidyl ether: reproduction, mutagenic, teratogenic, and cytogenic studies.
J B Terrill et al.
Toxicology and applied pharmacology, 64(2), 204-212 (1982-06-30)
D L Deforce et al.
Analytical biochemistry, 258(2), 331-338 (1998-05-08)
The in vitro adduct formation between phenyl glycidyl ether (PGE) and calf thymus DNA was investigated. Agarose slab gel electrophoresis of DNA incubated with PGE revealed that nearly all high-molecular-weight species were degraded after 10 h of incubation. After DNA
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