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143936

Sigma-Aldrich

Propionamide

97%

Synonym(s):

Propanamide, Propylamide

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About This Item

Linear Formula:
CH3CH2CONH2
CAS Number:
Molecular Weight:
73.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

bp

213 °C (lit.)

mp

76-79 °C (lit.)

solubility

alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
water: freely soluble

density

1.042 g/mL at 25 °C (lit.)

SMILES string

CCC(N)=O

InChI

1S/C3H7NO/c1-2-3(4)5/h2H2,1H3,(H2,4,5)

InChI key

QLNJFJADRCOGBJ-UHFFFAOYSA-N

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General description

Propionamide on γ-irradiation reacts with sulfur dioxide and this reaction has been studied by ESR spectroscopy, gas absorption measurements and X-ray diffraction.

Application

Propionamide was used as adsorbent in the determination of adsorption isotherms of acetamide and propionamide on multi-wall carbon nanotube. It was used in a robust screening method to study biotransformations using (+)-γ-lactamase enzyme.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Reactions of Gases with Irradiated Organic Solids: III. Reactions of Propionamide, n-Butyramide, Isobutyramide, Methacrylamide, Valeramide, and Stearamide with Sulfur Dioxide.
Perotti A, et al.
Mol. Cryst. Liq. Cryst., 9(1), 323-342 (2969)
Study of Adsorption Isotherms of Acetamide and Propionamide on Carbon Nanotube.
Vadi M and Moradi N.
Orient. J. Chem., 27(4), 1491-1491 (2011)
Ruth Oltenfreiter et al.
Nuclear medicine and biology, 31(4), 459-468 (2004-04-20)
Several studies have demonstrated a positive correlation between tumor progression and expression of extracellular proteinases such as matrix metalloproteinases (MMPs). MMP-2 and MMP-9 have become attractive targets for cancer research because of their increased expression in human malignant tumor tissues
Saranjit Singh et al.
Journal of pharmaceutical sciences, 91(1), 253-257 (2002-01-10)
The degradation behavior of famotidine (1) was investigated in 25% ammonia solution and in 2 M NaOH. The hydrolysis of the drug in ammonia resulted in separation of [3-[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]propionamide (3), an impurity listed in British Pharmacopoeia. The treatment with 2
D W Sickles et al.
Journal of neuroscience research, 46(1), 7-17 (1996-10-01)
Acrylamide (ACR) is an environmental toxicant and prototypic tool for studying mechanisms of peripheral neuropathies. Reductions in fast anterograde axonal transport (faAXT) are thought to be a critical step leading to axonal degeneration. Kinesin and microtubules (MT) were evaluated as

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