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Supelco

Discovery® C18 (5 µm) HPLC Columns

L × I.D. 2 cm × 4 mm HPLC guard Column Kit with 1 Cartridge holder + 1 Guard Cartridge

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About This Item

UNSPSC Code:
41115700

product name

Discovery® C18 Supelguard Guard Cartridge, Kit, 5 μm particle size, L × I.D. 2 cm × 4 mm

Agency

suitable for USP L1

Quality Level

packaging

pkg of 1 kit

technique(s)

HPLC: suitable

L × I.D.

2 cm × 4 mm

matrix active group

C18 (octadecyl) bonding phase

particle size

5 μm

pore size

180 Å

application(s)

food and beverages

compatibility

use to protect Discovery C18

separation technique

reversed phase

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General description

Discovery® C18 Supelguard Guard Cartridges [Kit, 5 μm particle size, L × I.D. 2 cm × 4 mm] contain a Discovery® packing, in a 2 cm stainless steel body, enclosed by polyether ether ketone (PEEK) encapsulated stainless steel frits (2 μm porosity). A Supelguard kit (one cartridge, a stand-alone holder, tubing, and 2 nuts and ferrules) enables one to use the cartridge with any analytical column. A direct-connect guard cartridge holder can directly connect a Supelguard cartridge to a Supelco analytical column. 3.0 mm cartridges are available in packs of two only-purchase a stand-alone or modular holder separately. Low volume 3.0 mm ID cartridges are a good choice for protecting an analytical column containing 3 μm particles.

Footnote

Kit includes one cartridge, a stand-alone holder, a piece of tubing, 2 nuts and ferrules.

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Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Fabrice Gritti et al.
Journal of chromatography. A, 1095(1-2), 27-39 (2005-11-09)
The adsorption isotherms of an ionizable compound, nortriptyline, were accurately measured by frontal analysis (FA) on a C(18)-Discovery column, first without buffer (in an aqueous solution of acetonitrile at 15%, v/v of ACN), then with a buffer (in 28%, v/v
T R Shantha Kumar et al.
Journal of pharmaceutical and biomedical analysis, 38(1), 173-179 (2005-05-24)
A simple, precise and accurate isocratic reverse-phase liquid chromatography method with programmed wavelength detection has been validated to quantify DRF-4367 and Phenol red, simultaneously for application in rat in situ single pass intestinal perfusion study to assess intestinal permeability of
Abbas Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(24), 2423-2429 (2011-07-26)
A novel isocratic reversed-phase high performance liquid-chromatography/ultraviolet detection method for simultaneous determination of cefdinir and cefixime in human plasma was developed and validated after optimization of various chromatographic conditions and other experimental parameters. Sample preparation based on a simple extraction
Himal Paudel Chhetri et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 22(5), 483-487 (2014-12-05)
This study presents the optimization of a simple HPLC-UV method for the determination of metformin in human plasma. Ion pair separation followed by UV detection was performed on deproteinized human plasma samples. The separation was carried out on a Discovery
Ramisetti Nageswara Rao et al.
Journal of separation science, 32(9), 1312-1322 (2009-04-29)
Modafinil, adrafinil and their related substances were synthesized and analyzed by RP-LC with ESI-MS/MS. The ionization mode, polarity, cone voltage, and chromatographic conditions were evaluated. The optimum LC-MS conditions to obtain fragment ions indispensable for identification of the structures were

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