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Key Documents

T5016

Sigma-Aldrich

Glyceryl tristearate

≥99%

Synonym(s):

TG(18:0/18:0/18:0), 1,2,3-Trioctadecanoylglycerol, Glycerol tristearate, Tristearin

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About This Item

Linear Formula:
[CH3(CH2)16COOCH2]2CHOCO(CH2)16CH3
CAS Number:
Molecular Weight:
891.48
Beilstein:
1718456
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Quality Level

Assay

≥99%

form

powder

functional group

ester

lipid type

neutral glycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C57H110O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h54H,4-53H2,1-3H3

InChI key

DCXXMTOCNZCJGO-UHFFFAOYSA-N

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Application


  • Rifabutin-loaded solid lipid nanoparticles for inhaled antitubercular therapy: Physicochemical and in vitro studies.: The research demonstrates the use of glyceryl tristearate in the development of rifabutin-loaded solid lipid nanoparticles, which shows promise for inhaled antitubercular therapy, suggesting an improvement in the therapeutic efficacy and reduction of systemic side effects (Gaspar DP et al., 2016).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Amir Malaki Nik et al.
Journal of agricultural and food chemistry, 60(16), 4126-4135 (2012-03-10)
The stability, crystallization, and melting behavior of canola stearin (CaSt) solid lipid nanoparticle dispersions (SLN) and canola oil-in-water emulsions (COE) with 10 wt % Poloxamer 188 (P188) or Tween 20 (T20) with and without 0.1 wt % β-carotene (BC) were
Xiao-Qiang Zou et al.
Journal of agricultural and food chemistry, 59(11), 6055-6063 (2011-05-17)
Human milk fat substitutes (HMFSs) were synthesized by lipozyme RM IM-catalyzed acidolysis of chemically interesterified palm stearin (mp = 58 °C) with mixed FAs from rapeseed oil, sunflower oil, palm kernel oil, stearic acid, and myristic acid in a solvent-free
Maike Windbergs et al.
International journal of pharmaceutics, 381(2), 184-191 (2009-09-29)
A monoacid triglyceride and a partial glyceride were extruded below their melting ranges alone and together in different mixture ratios to investigate the influence of the chemical composition of the lipid matrix on the solid-state properties and dissolution characteristics. The
Hanna Salminen et al.
Food chemistry, 141(3), 2934-2943 (2013-07-23)
A major challenge for food and pharmaceutical industries is the engineering of nanostructures that can efficiently encapsulate bioactive compounds with enhanced physical and chemical stability, and high load. The influence of surfactant properties on the physical and chemical stability of
Franco Pattarino et al.
International journal of pharmaceutics, 473(1-2), 87-94 (2014-06-28)
The work is aimed at investigating the polymorphism and the phase transition kinetics of binary lipid mixtures with potential application in controlled drug delivery. The lipid systems, constituted of glyceryl tristearate (GTS) added with different amounts (1.0-7.5% w/w) of a

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