O6254
(R)-(−)-2-Oxothiazolidine-4-carboxylic acid
≥98% (titration), suitable for plant cell culture
Synonym(s):
L-(−)-2-Oxothiazolidine-4-carboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C4H5NO3S
CAS Number:
Molecular Weight:
147.15
Beilstein:
4179169
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.26
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Product Name
(R)-(−)-2-Oxothiazolidine-4-carboxylic acid, ≥97% (TLC), ≥98% (titration)
Quality Level
Assay
≥97% (TLC)
≥98% (titration)
form
(powder to crystals)
technique(s)
cell culture | plant: suitable
color
white to off-white
SMILES string
OC(=O)[C@@H]1CSC(=O)N1
InChI
1S/C4H5NO3S/c6-3(7)2-1-9-4(8)5-2/h2H,1H2,(H,5,8)(H,6,7)/t2-/m0/s1
InChI key
BMLMGCPTLHPWPY-REOHCLBHSA-N
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Application
- Artificial elevation of glutathione contents in salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) reduces susceptibility to the powdery mildew pathogen Euoidium longipes.: This study explores the impact of enhanced glutathione levels on resistance to powdery mildew in tobacco plants deficient in salicylic acid, indicating a potential application of R-(−)-2-Oxothiazolidine-4-carboxylic acid in managing plant diseases (Künstler et al., 2020).
Biochem/physiol Actions
2-Oxothiazolidine-4-carboxylic acid augments glutathione and cysteine production.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Künstler et al.
Plant biology (Stuttgart, Germany), 22(1), 70-80 (2019-07-10)
The effects of elevated glutathione levels on defence responses to powdery mildew (Euoidium longipes) were investigated in a salicylic acid-deficient tobacco (Nicotiana tabacum cv. Xanthi NahG) and wild-type cv. Xanthi plants, where salicylic acid (SA) contents are normal. Aqueous solutions
Sandra Hodge et al.
American journal of respiratory cell and molecular biology, 44(5), 673-681 (2010-07-03)
Defective efferocytosis may perpetuate inflammation in smokers with or without chronic obstructive pulmonary disease (COPD). Macrophages may phenotypically polarize to classically activated M1 (proinflammatory; regulation of antigen presentation) or alternatively activated M2 (poor antigen presentation; improved efferocytosis) markers. In bronchoalveolar
María José Clemente-Moreno et al.
Plant, cell & environment, 36(3), 640-654 (2012-08-24)
Sharka, a disease caused by plum pox virus (PPV), has a significant economic impact on fruit tree production. In this work, we analysed the effect of (2,1,3)-benzothiadiazole (BTH) and L-2-oxo-4-thiazolidine-carboxylic acid (OTC) on plant growth and virus content. OTC reduced
T-H Lee et al.
International endodontic journal, 43(5), 430-435 (2010-06-04)
To evaluate the mechanisms of cytotoxicity of chlorhexidine (CHX) in human osteoblastic cells in vitro. Cytotoxicity, cell proliferation and collagen synthesis assays were performed to elucidate the toxic effects of CHX on the human osteoblastic cell line U2OS. To determine
Anna Vávrová et al.
Archives of toxicology, 85(5), 525-535 (2010-11-04)
The clinical usefulness of anthracycline antineoplastic drugs is limited by their cardiotoxicity. Its mechanisms have not been fully understood, although the induction of oxidative stress is widely believed to play the principal role. Glutathione is the dominant cellular antioxidant, while
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