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Key Documents

M1514

Sigma-Aldrich

Nω-Methyl-5-hydroxy­trypt­amine oxalate salt

≥90% (HPLC)

Synonym(s):

Nω-Methylserotonin oxalate salt

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About This Item

Empirical Formula (Hill Notation):
C11H14N2O · C2H2O4
CAS Number:
Molecular Weight:
280.28
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥90% (HPLC)

storage temp.

2-8°C

SMILES string

OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12

InChI

1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)

InChI key

DYOZWAJOUTVNAF-UHFFFAOYSA-N

Biochem/physiol Actions

Serotonin receptor ligand.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Albrecht Pfäfflin et al.
Annals of clinical biochemistry, 46(Pt 2), 146-148 (2009-01-20)
Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of paracetamol in therapeutic dosages
Sharla L Powell et al.
Journal of agricultural and food chemistry, 56(24), 11718-11726 (2008-12-04)
Cimicifuga racemosa (L.) Nutt. (syn. Actaea racemosa L., black cohosh) is used to relieve menopausal hot flashes, although clinical studies have provided conflicting data, and the active constituent(s) and mechanism(s) of action remain unknown. Because serotonergic receptors and transporters are
Niels Hadrup et al.
Drug and chemical toxicology, 42(1), 76-83 (2018-07-24)
Selenium (Se) nanoparticles have been proposed as food supplements. However, the particle formulation may exert unexpected toxicity. The aim was therefore to compare toxicity of low doses of Se nanoparticles and the dissolved, ionized Se species selenite. Female rats were
G L Laekeman et al.
Agents and actions, 16(5), 443-445 (1985-07-01)
Pharmacological effects of 5-hydroxykynuramine (5-HK) were investigated in chicken whole blood. It was shown that 5-HK had a time-depending inhibiting activity on platelet aggregation induced by 5-hydroxytryptamine (5-HT). Experiments were carried out in order to determine whether the inhibitory effect
D Alberghina et al.
Research in veterinary science, 90(3), 392-395 (2010-07-17)
To evaluate the changes in plasma and platelet serotonin (5-HT) as markers of the serotoninergic system in equines, 5-HT content was measured by high performance liquid chromatography (HPLC) in deproteinized plasma obtained from peripheral blood samples of 12 clinically healthy

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