L131

L-745,870 hydrochloride

• Synonym(s): 3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine hydrochloride
• Empirical Formula (Hill Notation): C₁₈H₁₉ClN₄ · HCl
• CAS Number: 1173023-36-3
• Molecular Weight: 363.28
• MDL number: MFCD01529971
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277918
• NACRES: NA.77

Properties

• form: solid
• Quality Level: 100
• color: white
• solubility: H₂O: 0.2 mg/mL; ethanol: 1.4 mg/mL; 0.1 M HCl: 5.5 mg/mL
• SMILES string: Cl.Clc1ccc(cc1)N2CCN(CC2)Cc3c[nH]c4ncccc34
• InChI: 1S/C18H19ClN4.ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;/h1-7,12H,8-11,13H2,(H,20,21);1H
• InChI key: GFFJYISJZJIKAF-UHFFFAOYSA-N
• Gene Information: human ... DRD4(1815)

Description

Biochem/physiol Actions

Selective D₄ dopamine receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold under license from Merck & Co., Inc., Kenilworth, NJ, U.S. for use solely for preclinical researchy purposes (i.e., not for the administration to or other use in humans).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves