Skip to Content
Merck
All Photos(6)

Key Documents

View All Documentation

G2878

Sigma-Aldrich

Glycocholic acid hydrate

synthetic, ≥97% (HPLC)

Synonym(s):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Cholylglycine, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)-glycine

Sign Into View Organizational & Contract Pricing
All Photos(6)

About This Item

Empirical Formula (Hill Notation):
C26H43NO6 · xH2O
CAS Number:
1192657-83-2
Molecular Weight:
465.62 (anhydrous basis)
Beilstein:
2955826
MDL number:
MFCD06408004
UNSPSC Code:
12161900
PubChem Substance ID:
24895107
NACRES:
NA.25

biological source

synthetic

Quality Level

200

description

anionic

Assay

≥97% (HPLC)

form

powder

mol wt

average mol wt 1000

aggregation number

2.1

technique(s)

enzyme immunoassay: suitable

CMC

7.1

functional group

amide

shipped in

ambient

storage temp.

room temp

SMILES string

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

InChI key

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system.

Biochem/physiol Actions

Bile Acid

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yazhou He et al.
PloS one, 9(3), e91202-e91202 (2014-03-14)
Association between the single nucleotide polymorphism rs3218536 (known as Arg188His) located in the X-ray repair cross complementing group 2 (XRCC2) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to
Raj S Bhopal et al.
The lancet. Diabetes & endocrinology, 2(3), 218-227 (2014-03-14)
The susceptibility to type 2 diabetes of people of south Asian descent is established, but there is little trial-based evidence for interventions to tackle this problem. We assessed a weight control and physical activity intervention in south Asian individuals in
Konstantin Kazankov et al.
Hepatology (Baltimore, Md.), 60(2), 521-530 (2014-03-14)
Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C
Jacqueline M Major et al.
The Journal of nutrition, 144(5), 729-733 (2014-03-14)
Vitamin E (α-tocopherol) plays a key role in the regulation of cell growth and differentiation and has been studied as a potential chemopreventive agent for prostate cancer. The association of serum vitamin E concentrations with cancer risk may be modified
Toshiharu Ninomiya
Current diabetes reports, 14(5), 487-487 (2014-03-14)
Growing epidemiologic evidence has suggested that people with diabetes mellitus are at an increased risk for the development of dementia. However, the results for the subtypes of dementia are inconsistent. This review examines the risk of dementia in people with
View All Related Papers

Protocols

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

HPLC Separation of Bile Acids with Ascentis Express C18

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

Related Content

Bile Acids Kit for LC-MS

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service