F5631
Fucoidan from Fucus vesiculosus
Crude
Synonym(s):
Fucoidin
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About This Item
Recommended Products
biological source
algae (Fucus Vesiculosus)
Quality Level
form
powder
quality
Crude
color
light yellow to brown
solubility
H2O: 10 mg/mL, clear to hazy, faintly yellow to brownish-yellow
cation traces
Ca: ≤1%
Na: ≤ 8% (ICP)
storage temp.
room temp
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General description
Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.
Application
Fucoidan from Fucus vesiculosus may be used as a biological response modifier and as a potential therapeutic agent with a wide range of biological activities. It may be used to study its pharmacokinetics, safety, efficacy and methods of delivery as a potential anticancer, anti-immune and anti-inflammatory agent. Fucoidan may be used to assess its potential and formulations for tissue engineering applications.
Biochem/physiol Actions
Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.
Preparation Note
Prepared by a modification of the method of Black, W.A.P., et al., J. Sci. Food Agri., 3, 122 (1952).
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Kazuo Azuma et al.
Marine drugs, 10(10), 2337-2348 (2012-11-22)
We evaluated the anti-tumor activities of the oral administration of fucoidan extracted from Cladosiphon okamuranus using a tumor (colon 26)-bearing mouse model. The materials used included low-molecular-weight fucoidan (LMWF: 6.5-40 kDa), intermediate-molecular-weight fucoidan (IMWF: 110-138 kDa) and high-molecular-weight fucoidan (HMWF:
Olesya S Vishchuk et al.
Food chemistry, 141(2), 1211-1217 (2013-06-26)
The sulfated polysaccharides from brown algae - the fucoidans - are known to be a topic of numerous studies, due to their beneficial biological activities including anti-tumour activity. In this study the effect of fucoidans isolated from brown algae Saccharina
Yong-Seok Han et al.
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Recently, the studies on the antiviral activities of marine natural products, especially marine polysaccharides, are attracting more and more attention all over the world. Marine-derived polysaccharides and their lower molecular weight oligosaccharide derivatives have been shown to possess a variety
Long Yu et al.
Food chemistry, 142, 197-200 (2013-09-05)
Structure of fucoidan from sea cucumber Acaudina molpadioides (Am-FUC) was investigated in this study. Low molecular weight polysaccharide of Am-FUC (Am-LMW) was prepared by enzymatic degradation and assayed by nuclear magnetic resonance. According to the structure of Am-LMW, and referring
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