C0563
Cardiolipin sodium salt from bovine heart
≥97% (TLC), lyophilized powder
Synonym(s):
Diphosphatidylglycerol
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![14:0 Cardiolipin (sodium salt) 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt), powder](/deepweb/assets/sigmaaldrich/product/images/390/523/992bed4e-3608-4209-aa6e-fa9206a4a31b/640/992bed4e-3608-4209-aa6e-fa9206a4a31b.jpg)
biological source
bovine heart
Quality Level
Assay
≥97% (TLC)
form
lyophilized powder
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
General description
Cardiolipin is localized in the inner membrane of mitochondria. It contains 18 carbon atoms, 3-phosphatidyl groups connected via a glycerol bridge. Cardiolipin is an important component of ATP synthase enzyme.
Application
Cardiolipin sodium salt from bovine heart has been used:
- as a phospholipid standard in thin layer chromatography for the quantification of total mitochondrial lipids of Neurospora crassa(89)
- as an internal standard in reverse phase high performance liquid chromatography (RP-HPLC) for quantification of bacterial lipid extracts(90)
- as an antigen to evaluate IgM reaction in systemic lupus erythematosus (SLE) patients(91)
Biochem/physiol Actions
Cardiolipin is a mitochondrial phospholipid that is found in mammalian tissues in low concentrations. It is often a membrane component. Inhibits cell attachment of fibronectin, vitronectin and Type I collagen.
Packaging
packaged under argon
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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