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Key Documents

AV39691

Sigma-Aldrich

Anti-ZNF397 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Zinc finger protein 397

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

31 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_115723

UniProt accession no.

Q8NF99-2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ZNF397(84307)

General description

ZNF397 is a centromeric zinc finger protein that has a SCAN domain and functions as a transcriptional regulator. It has been classified as an interphase to early prophase-specific protein in mammals.
Rabbit Anti-ZNF397 antibody recognizes human ZNF397.

Immunogen

Synthetic peptide directed towards the C terminal region of human ZNF397

Application

Rabbit Anti-ZNF397 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml and for IHC at 4-8 μg/ml.

Biochem/physiol Actions

ZNF397 belongs to the krueppel C2H2-type zinc-finger protein family. This gene product, isoform 3, acts as a DNA-dependent transcriptional repressor.

Sequence

Synthetic peptide located within the following region: SAIRWECVSPGSFPGDIIAAEATHSTISCFAINTLPATILPSKNVNRKYF

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC10407

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S L Bailey et al.
Chromosoma, 117(4), 367-380 (2008-03-29)
The centromere is a complex structure required for equal segregation of newly synthesised sister chromatids at mitosis. One of the significant objectives in centromere research is to determine the complete repertoire of protein components that constitute the kinetochore. Here, we

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