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Key Documents

63590

Sigma-Aldrich

May-Grünwald solution

for the staining of blood constituents

Synonym(s):

Eosin – methylene blue solution, Eosin methylene blue according to May-Grünwald

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About This Item

MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.25

grade

for the staining of blood constituents

Quality Level

technique(s)

microbe id | staining: suitable

impurities

methanol

density

0.80 g/mL at 20 °C

suitability

Chlamydia spp.
Histoplasma spp.
Plasmodium spp.
Trichomonas spp.
bacteria
protozoa
spirochetes

SMILES string

[K+].COC(=O)c1ccccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c([O-])c(Br)cc24

InChI

1S/C21H10Br4O5.K/c1-29-21(28)9-5-3-2-4-8(9)14-10-6-12(22)17(26)15(24)19(10)30-20-11(14)7-13(23)18(27)16(20)25;/h2-7,26H,1H3;/q;+1/p-1

InChI key

NXBZXYJXNIFCRJ-UHFFFAOYSA-M

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Application

May-Grünwald solution (Eosin – methylene blue solution) is used with Giemsa stain for histological staining of blood cells.

Other Notes

Stain for the panoptic staining according to Pappenheim

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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V Hofman et al.
Cytopathology : official journal of the British Society for Clinical Cytology, 23(1), 30-38 (2011-01-08)
Recurrence rates after surgery for non-small cell lung cancer (NSCLC) range from 25 to 50% and 5-year survival is only 60-70%. Because no biomarkers are predictive of recurrence or the onset of metastasis, pathological TNM (pTNM) staging is currently the
P. Bock, ed.
Romeis Mikroskopische Technik null
Elsa Beraki et al.
CytoJournal, 9, 8-8 (2012-05-11)
Protocols for immunocytochemical staining (ICC) and in situ hybridization (ISH) of air-dried Diff-Quick or May-Grünwald Giemsa (MGG)-stained smears have been difficult to establish. An increasing need to be able to use prestained slides for ICC and ISH in specific cases
Farshad Naghshvar et al.
Cell biochemistry and function, 30(7), 569-573 (2012-04-27)
The protective effects of carnosine as a natural dipeptide were investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were injected with solutions of carnosine at three different doses (10, 50 and 100 mg kg(-1) bw) for
Michał Zimecki et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 61(11), 1247-1255 (2012-07-20)
The aim of this study was to assess the utility of lactoferrin (LF), a natural immunomodulator, to restrain allergen-induced pleurisy in mice. BALB/c female mice, 8- to 10-week old, weighing 24 g on average, were used. Mice were immunized intraperitoneally

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