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22141

Sigma-Aldrich

Celite® 545 AW

filter aid, acid washed, treated with sodium carbonate, flux calcined

Synonym(s):

Diatomaceous earth, flux-calcined

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About This Item

CAS Number:
68855-54-9
MDL number:
MFCD00132803
UNSPSC Code:
11101527
PubChem Substance ID:
329752267
NACRES:
SB.54

Quality Level

100

form

powder

quality

acid washed
flux calcined
treated with sodium carbonate

composition

Al2O3, 4.0%
CaO, 0.5%
Fe2O3, 1.3%
Na2O + K2O, 3.3%
SiO2, 89.5%

loss

~0.3% loss on ignition, 900 °C

particle size

≤113 μm (82% (acc. to Cilas))

pH

<7 (25 °C, 10% in aq. suspension)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Diatomaceous earth is made up of natural amorphous silica formed from the fossilized skeletons of diatoms. It is extracted, crushed, dried and calcined with flux material. DE is widely used as filler in construction materials, paints and as an anti-caking agent for agricultural chemicals. It has high water and oil absorption ability.

Application

Diatomaceous earth may be used as an adsorbent for column chromatography.

Caution

Not Intended for cGMP Parenteral Pharmaceutical Manufacturing

Legal Information

Celite is a registered trademark of Imerys Minerals California, Inc.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tobias Odenwald et al.
Journal of the American Society of Nephrology : JASN, 17(3), 655-662 (2006-01-20)
A previous study in subtotally nephrectomized (SNX) rats suggested beneficial effects of the calcimimetic R-568 beyond the control of mineral metabolism. This study analyzed potential blood pressure (BP)-lowering effects of R-568. Male Sprague-Dawley rats received two-stage subtotal nephrectomy or sham
Production of structured triacylglycerols (STAG) rich in docosahexaenoic acid (DHA) in position 2 by acidolysis of tuna oil catalyzed by lipases.
Hita E, et al.
Process. Biochem., 42(3), 415-422 (2007)
Caroline Schirpenbach et al.
Clinical chemistry, 52(9), 1749-1755 (2006-07-22)
Measurements of aldosterone have become more common since the recognition that primary aldosteronism is a more frequent cause of hypertension than previously believed. Our aim was to compare concentrations reported by 4 assays for samples obtained after saline infusion during
H Checkoway et al.
British journal of industrial medicine, 50(7), 586-597 (1993-07-01)
A cohort mortality study was conducted among workers from two plants in the diatomaceous earth mining and processing industry in California. Diatomaceous earth consists of the skeletal remains of diatoms. Exposure to amorphous (non-crystalline) and crystalline silica in the form
Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides.
Journal of cellular and molecular medicine (2015).
Liu JS, et al.
Journal of Cellular and Molecular Medicine, 19(7), 1697-1709 (2015)
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