Skip to Content
Merck
All Photos(3)

Key Documents

58698

Supelco

N-Isobutyryl-L-cysteine

for chiral derivatization, LiChropur, ≥97.0%

Synonym(s):

N-(2-Methylpropionyl)-L-cysteine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C7H13NO3S
CAS Number:
Molecular Weight:
191.25
MDL number:
UNSPSC Code:
12000000
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

grade

for chiral derivatization

Quality Level

product line

ChiraSelect

Assay

≥97.0% (RT)
≥97.0%

form

solid

optical purity

enantiomeric ratio: ≥99.5:0.5 (HPLC)

quality

LiChropur

technique(s)

HPLC: suitable

mp

97-101 °C

storage temp.

2-8°C

SMILES string

CC(C)C(=O)N[C@@H](CS)C(O)=O

InChI

1S/C7H13NO3S/c1-4(2)6(9)8-5(3-12)7(10)11/h4-5,12H,3H2,1-2H3,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

BWBQXMAXLAHHTK-YFKPBYRVSA-N

Looking for similar products? Visit Product Comparison Guide

General description

N-Isobutyryl-L-cysteine is a chiral derivatizing agent, widely used for the separation of amino acid enantiomers.

Application

N-Isobutyryl-L-cysteine may be used as a chiral derivatization agent for the determination of D- and L-amino acids in natural/synthetic bioactive peptides, pharmaceutical formulations and absolute configuration of selenomethionine using chromatography techniques.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Chiral derivatizing agent employed in the assay of the enantiomeric purity of amino acids with OPA

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

ChiraSelect is a trademark of Sigma-Aldrich Co. LLC
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

H. Bruckner et al.
Journal of Chromatography A, 666, 259-259 (1994)
Yuta Mutaguchi et al.
Frontiers in microbiology, 9, 1540-1540 (2018-07-31)
Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic acid bacteria carrying homologs to ILEP. Twelve
H Brückner et al.
Journal of chromatography, 476, 73-82 (1989-08-04)
The enantioseparation of standard mixtures composed of protein DL-amino acids was performed by reversed-phase high-performance liquid chromatography of the corresponding diastereomeric isoindolyl derivatives, formed by automated precolumn derivatization with o-phthaldialdehyde (OPA) and a series of N-acyl-L-cysteines(Acyl-Cys). A photodiode-array detector, operating
Liquid chromatographic determination of d-and l-amino acids by derivatization with o-phthaldialdehyde and N-isobutyryl-l-cysteine applications with reference to the analysis of peptidic antibiotics, toxins, drugs and pharmaceutically used amino acids
Bruckner H, et al.
Journal of Chromatography A, 711(1), 201-215 (1995)
M.A. Blaskovich et al.
Journal of the American Chemical Society, 115, 5021-5021 (1993)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service