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2-Ethylhexyl salicylate

analytical standard

Synonym(s):

2-Ethylhexyl 2-hydroxybenzoate, Octisalate, Octyl salicylate

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About This Item

Linear Formula:
(HO)C6H4CO2CH2CH(C2H5)(CH2)3CH3
CAS Number:
Molecular Weight:
250.33
Beilstein:
2730664
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n/D 1.501-1.503
n20/D 1.502 (lit.)

bp

189-190 °C/21 mmHg (lit.)

density

1.014 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

SMILES string

CCCCC(CC)COC(=O)c1ccccc1O

InChI

1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3

InChI key

FMRHJJZUHUTGKE-UHFFFAOYSA-N

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General description

2-Ethylhexyl salicylate is used as a UV filter in sunscreens.

Application

2-Ethylhexyl salicylate may be used as a reference standard for the determination of octyl salicylate as a UV filter authorized in sunscreens by high-performance liquid chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Environment

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

323.6 °F - closed cup

Flash Point(C)

162 °C - closed cup


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A DFT Investigation of the Molecular Structure and UV Absorption Spectra of 2-Ethylhexyl 2-Hydroxybenzoate (Octisalate) and Meta-Substituted 2-Ethylhexyl 2-Hydroxybenzoate: Sunscreen Applications
Punyain W.
Applied Mechanics and Materials, 855, 15-21 (2017)
Development and Validation of RP-HPLC Method for Analysis of Four UV Filters in Sunscreen Products.
NAY, et al.
International Journal of Pharmaceutical Sciences Review and Research, 23(2), 254-258 (2013)
Determination of the UV filters worldwide authorised in sunscreens by high-performance liquid chromatography: use of cyclodextrins as mobile phase modifier.
Chisvert A, et al.
Journal of Chromatography A, 921(2), 207-215 (2001)
M McVean et al.
Molecular carcinogenesis, 24(3), 169-176 (1999-04-16)
Topical application of alpha-tocopherol (alphaTH), the most prominent naturally occurring form of vitamin E, inhibits ultraviolet (UV) B-induced photocarcinogenesis and DNA photodamage in C3H mice in vivo. In this study, we compared alphaTH with other vitamin E compounds and with
M McVean et al.
Carcinogenesis, 18(8), 1617-1622 (1997-08-01)
Ultraviolet B (UVB, 290-320 nm) exposure results in a variety of cellular insults including induction of cyclobutane pyrimidine dimers in DNA. Accumulation of these lesions can lead to mutations in critical genes and contribute to the development of nonmelanoma skin

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