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28125

Sigma-Aldrich

18-Crown-6

purum, ≥99.0% (GC)

Synonym(s):

18C6, 1,4,7,10,13,16-Hexaoxacyclooctadecane

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About This Item

Empirical Formula (Hill Notation):
C12H24O6
CAS Number:
Molecular Weight:
264.32
Beilstein:
1619616
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

grade

purum

Quality Level

Assay

≥99.0% (GC)

form

solid

mp

38-41 °C
42-45 °C (lit.)

functional group

ether

SMILES string

O1CCOCCOCCOCCOCCOCC1

InChI

1S/C12H24O6/c1-2-14-5-6-16-9-10-18-12-11-17-8-7-15-4-3-13-1/h1-12H2

InChI key

XEZNGIUYQVAUSS-UHFFFAOYSA-N

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Application

18-Crown-6 can be used as a model for crown ethers to study the effect of acid-base properties of mixed solvent on their solution enthalpy.It is generally used as a phase transfer catalyst and a complexing agent. It specifically binds to potassium ion, ammonium or protonated alkyl amines to form complexes.
Can be useful as phase-transfer catalysts.

Other Notes

Macrocyclic polyethers with repeating (-CH2CH2O) units. The compounds are ionophoric (form stable complexes with cations).
Phase transfer catalyst, complexing-agent

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Counter cation-controlled air oxidation of manganese derivatives of tetrachlorocatechol.
Ruiz R, et al.
Inorganic Chemistry Communications, 3(2), 76-79 (2000)
Lower rim calix (4) arene ketone derivatives and their interaction with alkali metal cations. Structural and thermodynamic (solution and complexation) characterisation of the tetraphenyl ketone derivative and its sodium complex.
de Namor AFD, et al.
Physical Chemistry Chemical Physics, 3(18), 4010-4021 (2001)
Effect of base-acid properties of the mixtures of water with methanol on the solution enthalpy of selected cyclic ethers in this mixture at 298.15 K.
Jozwiak M and Warczakowska A
Journal of Thermal Analysis and Calorimetry, 121(2), 765-770 (2015)
Chiral separations by host-guest complexation with cyclodextrin and crown ether in capillary zone electrophoresis.
Kuhn R, et al.
Chromatographia, 33(1-2), 32-36 (1992)
F. Vogtle et al.
Topics in Current Chemistry, 98 (1981)

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