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04238

Sigma-Aldrich

Hydroxyapatite

puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
EC Number:
215-145-7
MDL number:
MFCD00010904
UNSPSC Code:
41116107
PubChem Substance ID:
57646735
NACRES:
NA.21

grade

puriss.

Quality Level

200

Assay

≥90% (calculated on glowed substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, FCC, E341

composition

Ca, 35-40%

impurities

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% insoluble in HCl

loss

≤8% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤1500 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤5000 mg/kg

cation traces

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Hg: ≤1 mg/kg
Pb: ≤2 mg/kg
Zn: ≤20 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Application


  • New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites.: This research article focuses on the development and characterization of magnesium-doped hydroxyapatite within a dextran matrix, emphasizing its potential applications in biomedical and tissue engineering fields (Predoi et al., 2023).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3789
BCCK3981
BCCG0883
BCCF4218
BCCD1627

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Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
Bjarke Viberg et al.
Acta orthopaedica, 84(3), 254-259 (2013-04-19)
Elderly patients with displaced femoral neck fractures are commonly treated with a hemiarthroplasty (HA), but little is known about the long-term failure of this treatment. We compared reoperation rates for patients aged at least 75 years with displaced femoral neck
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