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AB15766

Sigma-Aldrich

Anti-Sox1 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, rodent, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_005986.2

UniProt accession no.

O00570

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SOX1(6656)

Specificity

Reactivity with other species has not been confirmed.
Recognizes Sox-1, a high mobility group (HMG) transcription factor.

Immunogen

Synthetic peptide from human Sox1.

Application

Anti-Sox1 Antibody detects level of Sox1 & has been published & validated for use in WB, IH.
Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience
Western blot: 1:200-1:1,000 using ECL. Immunohistochemistry: 1:200-1:1,000. Optimal working dilutions must be determined by the end user.

Linkage

Replaces: AB5768

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Format: Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Catarina M Seabra et al.
Molecular autism, 11(1), 45-45 (2020-06-07)
MBD5, encoding the methyl-CpG-binding domain 5 protein, has been proposed as a necessary and sufficient driver of the 2q23.1 microdeletion syndrome. De novo missense and protein-truncating variants from exome sequencing studies have directly implicated MBD5 in the etiology of autism
Jing Liu et al.
Stem cell reviews and reports, 8(4), 1129-1137 (2012-10-12)
microRNAs (miRNAs) are important modulators in regulating gene expression at the post-transcriptional level and are therefore emerging as strong mediators in neural fate determination. Here, by use of the model of human embryonic stem cell (hESC)-derived neurogenesis, miRNAs involved in
Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice.
Burel-Vandenbos, F; Turchi, L; Benchetrit, M; Fontas, E; Pedeutour, Z; Rigau, V; Almairac et al.
Neuro-Oncology null
Ying Pei et al.
Brain research, 1638(Pt A), 57-73 (2015-08-10)
Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique source of human primary cells for toxicity screens. Here, we report on the comparative cytotoxicity of 80 compounds (neurotoxicants, developmental neurotoxicants, and environmental compounds) in iPSC as well
E Tian et al.
Cell reports, 16(3), 781-792 (2016-07-12)
Growing evidence indicates important roles for astrocytes in neurodevelopment and diseases. However, astrocytes and their roles in these processes remain poorly understood. Despite recent progress in reprogramming somatic cells into different types of neural cells, reprogramming to astrocytes has lagged.
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