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Key Documents

AB1128

Sigma-Aldrich

Anti-Respiratory Syncytial Virus Antibody

Chemicon®, from goat

Synonym(s):

RSV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

shipped in

wet ice

Specificity

Recognizes RSV, all antigens. Does not react with Para 1-3, Influenza A & B and Adenovirus by IFA. Non reactive with HEp-2 cells and WI-38 cells.

Immunogen

Human RSV isolate

Application

Anti-Respiratory Syncytial Virus Antibody is an antibody against Respiratory Syncytial Virus for use in ELISA, IF, IH(P).
Indirect immunofluorescence: 1:480.

Reactive in paraffin embedded sections (see matsuse, et al 2000).

ELISA: 1:10,000

Fusion inhibition (1:256)

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin in PBS (0.01 M, pH 7.2) with 0.1% sodium azide.

Storage and Stability

Maintain -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Recurrent respiratory syncytial virus infections in allergen-sensitized mice lead to persistent airway inflammation and hyperresponsiveness.
H Matsuse, A K Behera, M Kumar, H Rabb, R F Lockey, S S Mohapatra
Journal of immunology (Baltimore, Md. : 1950) (1950)
Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells.
San-Juan-Vergara, H; Peeples, ME; Lockey, RF; Mohapatra, SS
Journal of virology null
Nanobodies? specific for respiratory syncytial virus fusion protein protect against infection by inhibition of fusion.
Schepens, B; Iba?ez, LI; De Baets, S; Hultberg, A; Bogaert, P; De Bleser, P; Vervalle et al.
The Journal of Infectious Diseases null
Respiratory syncytial virus glycoproteins uptake occurs through clathrin-mediated endocytosis in a human epithelial cell line.
Abel Gutierrez-Ortega,Carla Sanchez-Hernandez,Beatriz Gomez-Garcia
Virology Journal null
Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation.
Webster Marketon, JI; Corry, J
FEBS Open Bio null

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