1.47574

di-Sodium hydrogen phosphate heptahydrate

granulated, DAC, USP, EMPROVE^® EXPERT

• Synonym(s): Sodium phosphate dibasic heptahydrate, Disodium hydrogen phosphate heptahydrate, Disodium phosphate
• Linear Formula: Na₂HPO₄ · 7H₂O
• CAS Number: 7782-85-6
• Molecular Weight: 268.07
• MDL number: MFCD00149180

Properties

• Agency: DAC; USP
• Quality Level: 500
• vapor density: 4.9 (vs air)
• product line: EMPROVE^® EXPERT
• form: granular
• impurities: low in endotoxins
• density: 1.68 g/mL at 25 °C (lit.)
• application(s): liquid formulation; parenterals; pharma/biopharma processes; pharma/biopharma processes; pharma/biopharma processes
• storage temp.: 15-25°C
• SMILES string: O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O
• InChI: 1S/2Na.H3O4P.7H2O/c;;1-5(2,3)4;;;;;;;/h;;(H3,1,2,3,4);7*1H2/q2*+1;;;;;;;;/p-2
• InChI key: PYLIXCKOHOHGKQ-UHFFFAOYSA-L

Description

General description

Standard bulk materials often show a tendency for caking, clumping and dust formation which results in laborious weighing and manual de-caking processes with a negative impact on manufacturing efficiency. Due to its granulated form, di-Sodium hydrogen phosphate heptahydrate granulated is free-flowing and easy to handle. Its greatly reduced caking behavior facilitates processability, speeds up manufacturing processes and increases operator safety. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

di-Sodium hydrogen phosphate heptahydrate is used as a buffer component for Biomolecule downstream processing steps and final formulation as well as small molecule final formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany