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P-077

Supelco

Propofol-D17 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C12D17HO
CAS Number:
1261393-54-7
Molecular Weight:
195.38
EC Number:
200-659-6
MDL number:
MFCD10001682
UNSPSC Code:
41116107
PubChem Substance ID:
329820054
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

OC1=C(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C1C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3/i1D3,2D3,3D3,4D3,5D,6D,7D,8D,9D

InChI key

OLBCVFGFOZPWHH-ACWNEFEHSA-N

General description

Propofol, also known as Diprivan®, is a short-acting, hypnotic drug intravenously administered for the induction and maintenance of general anesthesia and sedation. This internal standard is suitable for a variety of uses including forensic and forensic toxicology analysis, isotope dilution methods, calibrator preparation, and drug monitoring in plasma or whole blood.

Application


  • Propofol-D₁₇ in forensic analysis: Propofol-D₁₇ was utilized to confirm testimonial evidence in serial homicide cases through drug detection in decomposed cadavers, demonstrating its value in complex forensic scenarios (Ottaviano et al., 2021).

  • Pharmacokinetic studies with Propofol-D₁₇: A sensitive LC-APCI-MS/MS method was developed using Propofol-D₁₇ to quantify propofol in a bioequivalence study among healthy Chinese subjects, enhancing understanding of its pharmacokinetics (Tang et al., 2020).

  • Evaluation of analytical methods using Propofol-D₁₇: Comparative analysis of LC-MS/MS and GC-MS for propofol detection highlights Propofol-D₁₇′s role in improving analytical procedures for forensic and clinical toxicology (Vaiano et al., 2015).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Diprivan is a registered trademark of Abraxis Bioscience, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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