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850757C

Avanti

16:0-18:1 PE

Avanti Research - A Croda Brand

Synonym(s):

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; POPE; PE(16:0/18:1(9Z)); 110637

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About This Item

Empirical Formula (Hill Notation):
C39H76NO8P
CAS Number:
Molecular Weight:
718.00
UNSPSC Code:
51191904
NACRES:
NA.25

description

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine, chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850757C-25mg)
pkg of 2 × 20 mL (850757C-1g)
pkg of 2 × 4 mL (850757C-200mg)
pkg of 5 × 4 mL (850757C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (850757C-25mg)
25 mg/mL (850757C-1g)
25 mg/mL (850757C-200mg)
25 mg/mL (850757C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-

InChI key

FHQVHHIBKUMWTI-ZCXUNETKSA-N

Application

16:0-18:1 PE has been used as a synthetic lipid for the preparation of liposomes.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850757C-1g)
5 mL Clear Glass Sealed Ampule (850757C-200mg)
5 mL Clear Glass Sealed Ampule (850757C-25mg)
5 mL Clear Glass Sealed Ampule (850757C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ionization Properties of Phospholipids Determined by Zeta Potential Measurements
Sathappa M and Alder NN
Bio-protocol, 6(22) (2016)
Mitochondria: Practical Protocols (2018)
Mariya Chavarha et al.
Langmuir : the ACS journal of surfaces and colloids, 28(48), 16596-16604 (2012-11-13)
Prior studies have shown that the biological mixture of the two hydrophobic surfactant proteins, SP-B and SP-C, produces faster adsorption of the surfactant lipids to an air/water interface, and that they induce 1-palmitoyl-2-oleoyl phosphatidylethanolamine (POPE) to form inverse bicontinuous cubic
Charles G Cranfield et al.
Langmuir : the ACS journal of surfaces and colloids, 33(26), 6630-6637 (2017-06-14)
Cyclotides are cyclic disulfide-rich peptides that are chemically and thermally stable and possess pharmaceutical and insecticidal properties. The activities reported for cyclotides correlate with their ability to target phosphatidylethanolamine (PE)-phospholipids and disrupt cell membranes. However, the mechanism by which this
Sónia Troeira Henriques et al.
Journal of the American Chemical Society, 141(51), 20460-20469 (2019-11-26)
Peptides with pharmaceutical activities are attractive drug leads, and knowledge of their mode-of-action is essential for translation into the clinic. Comparison of native and enantiomeric peptides has long been used as a powerful approach to discriminate membrane- or receptor-mediated modes-of-action

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