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841188P

Avanti

E. coli PG

Avanti Research™ - A Croda Brand 841188P, powder

Synonym(s):

L-α-phosphatidylglycerol (E. coli) (sodium salt)

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About This Item

CAS Number:
796963-92-3
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (841188P-10mg)
pkg of 1 × 25 mg (841188P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 841188P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCC(C1)C1CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

General description

Phosphatidylglycerol (PG) is a membrane lipid found in the inner membrane of E. coli.

Application

E. coli PG or L-α-phosphatidylglycerol (E. coli) (sodium salt) might be used:
  • as a lipid antigen to trigger human T cell response
  • as a standard in mass spectrometry (MS) of mammalian cell entry (MCE) proteins bound to phosphatidylglycerol (PG)
  • in bacterial model membranes to evaluate the lipid-lipid interactions and to serve potentially as a model for validation of novel

Packaging

5 mL Clear Glass Sealed Ampule (841188P-10mg)
5 mL Clear Glass Sealed Ampule (841188P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adam Shahine et al.
Science immunology, 2(16) (2017-10-22)
Human T cell autoreactivity toward lipid antigens presented by CD1 proteins can manifest in numerous diseases, including psoriasis, contact hypersensitivities, and allergies. However, the molecular mechanisms for regulating T cell autoreactivity toward lipid antigens remain unclear. We determined the basis
Damian C Ekiert et al.
Cell, 169(2), 273-285 (2017-04-08)
How phospholipids are trafficked between the bacterial inner and outer membranes through the hydrophilic space of the periplasm is not known. We report that members of the mammalian cell entry (MCE) protein family form hexameric assemblies with a central channel
Mikhail Bogdanov et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(34), 15057-15062 (2010-08-11)
Phosphatidylcholine (PC) has been widely used in place of naturally occurring phosphatidylethanolamine (PE) in reconstitution of bacterial membrane proteins. However, PC does not support native structure or function for several reconstituted transport proteins. Lactose permease (LacY) of Escherichia coli, when
Javier Hoyo et al.
General physiology and biophysics, 39(2), 195-202 (2020-04-25)
The current strategies to eradicate bacteria require that the antimicrobial agent either penetrate or disrupt the bacterial membrane. In Escherichia coli (E.coli) as a model of Gram-negative strains, the antimicrobials have to cross two barriers - the outer and the
Ildiko Van Rhijn et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(2), 380-385 (2015-12-02)
In contrast with the common detection of T cells that recognize MHC, CD1a, CD1c, or CD1d proteins, CD1b autoreactive T cells have been difficult to isolate in humans. Here we report the development of polyvalent complexes of CD1b proteins and

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