W325104

2-Acetylpyridine

≥99%, FG

• Synonym(s): Methyl 2-pyridyl ketone
• Empirical Formula (Hill Notation): C₇H₇NO
• CAS Number: 1122-62-9
• Molecular Weight: 121.14
• FEMA Number: 3251
• Beilstein: 107759
• EC Number: 214-355-6
• Council of Europe no.: 2315
• MDL number: MFCD00006303
• UNSPSC Code: 12164502
• PubChem Substance ID: 24901587
• Flavis number: 14.038
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: FG; Fragrance grade; Halal; Kosher
• Agency: follows IFRA guidelines; meets purity specifications of JECFA
• reg. compliance: EU Regulation 1223/2009; EU Regulation 1334/2008 & 178/2002
• Assay: ≥99%
• form: liquid
• refractive index: n20/D 1.521 (lit.)
• bp: 188-189 °C (lit.)
• density: 1.08 g/mL at 25 °C (lit.)
• application(s): flavors and fragrances
• Documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• fragrance allergen: no known allergens
• Organoleptic: corn; fatty; oily; popcorn; tobacco
• SMILES string: CC(=O)c1ccccn1
• InChI: 1S/C7H7NO/c1-6(9)7-4-2-3-5-8-7/h2-5H,1H3
• InChI key: AJKVQEKCUACUMD-UHFFFAOYSA-N

Description

General description

2-Acetylpyridine is a volatile flavor compound found in rye bread crust and roasted sesame. It has also been identified as a key contributor to the “scented rice”-like aroma in Yahonkaoluo leaves and Xiangjing-8618 rice.

Application

• Interaction with CT-DNA and in vitro cytotoxicity of two new copper(II)-based potential drugs derived from octanoic hydrazide ligands.: This study investigates the interaction of copper(II) complexes, derived from octanoic hydrazide ligands including 2-Acetylpyridine, with CT-DNA and their cytotoxic effects. The results indicate significant potential for these complexes as anticancer agents (Chowdhury et al., 2024).


• Three water-soluble copper(II) N-heterocyclic carbene complexes: toward copper-catalyzed ketone reduction under sustainable conditions.: This research explores the synthesis and application of water-soluble copper(II) complexes, including those containing 2-Acetylpyridine, for catalyzing ketone reductions under sustainable conditions. The study emphasizes the potential for green chemistry applications (Sharma et al., 2024).


• Eco-friendly Cu/NiO nanoparticle synthesis: Catalytic potential in isatin-based chalcone synthesis for anticancer activity.: The study focuses on the synthesis of Cu/NiO nanoparticles, incorporating 2-Acetylpyridine, for their catalytic efficacy in the synthesis of chalcones with potential anticancer properties (Cahyana et al., 2023).


• The Application of Synthetic Flavors in Zebrafish (Danio rerio) Rearing with Emphasis on Attractive Ones: Effects on Fish Development, Welfare, and Appetite.: This research investigates the impact of synthetic flavors, including 2-Acetylpyridine, on zebrafish development, welfare, and appetite, highlighting potential applications in aquaculture (Conti et al., 2023).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315
• Precautionary Statements: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): 163.4 °F - closed cup
• Flash Point(C): 73 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves