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Key Documents

P42800

Sigma-Aldrich

2-Picolinic acid

ReagentPlus®, 99%

Synonym(s):

α-Picolinic acid, Pyridine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
Molecular Weight:
123.11
Beilstein:
109595
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

product line

ReagentPlus®

Assay

99%

form

crystals

reaction suitability

reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

mp

139-142 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccccn1

InChI

1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)

InChI key

SIOXPEMLGUPBBT-UHFFFAOYSA-N

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Application

Chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Transition Met. Chem. (London), 19, 521-521 (1994)
Orient. J. Chem., 9, 43-43 (1993)
Orient. J. Chem., 9, 60-60 (1993)
Monatshefte fur Chemie / Chemical Monthly, 125, 833-833 (1994)
L Varesio et al.
Journal of immunology (Baltimore, Md. : 1950), 145(12), 4265-4271 (1990-12-15)
We have studied the effects of picolinic acid, a product of tryptophan degradation, on the activation of mouse peritoneal macrophages (M phi). Picolinic acid acts synergistically with IFN-gamma in activating M phi from C57BL/6 mice. Moreover, M phi from C3H/HeJ

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