P2139
Poly(ethylene glycol)
average MN 8,000, hydroxyl
Synonym(s):
Polyethylene glycol, PEG
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About This Item
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
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product name
Poly(ethylene glycol), average mol wt 8,000, powder
form
powder
Quality Level
mol wt
average mol wt 8,000
solubility
water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)
density
1.0845 g/mL at 70 °C
1.0689 g/mL at 90 °C
Ω-end
hydroxyl
α-end
hydroxyl
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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General description
Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response
Application
Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.
PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.
PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.
PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.
PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.
Features and Benefits
- Highstructural flexibility
- Biocompatibility
- Amphiphilicity
- Highhydration capacity
- Devoidof any steric hindrance
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Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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