Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

K2755

Sigma-Aldrich

2-Keto-3-deoxyoctonate ammonium salt

≥97%

Synonym(s):

3-Deoxyoctulosonic acid, KDO

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
C8H14O8 · NH3
CAS Number:
103404-70-2
Molecular Weight:
255.22
MDL number:
MFCD00057549
UNSPSC Code:
12352100
PubChem Substance ID:
57654316
NACRES:
NA.22

Quality Level

200

Assay

≥97%

form

powder

storage temp.

−20°C

SMILES string

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3

InChI key

UDJBBKGYARWWNJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

  • Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Biochem/physiol Actions

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000327402
0000327401
0000327400
0000286675
0000286674

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Laura Cipolla et al.
Current drug discovery technologies, 6(1), 19-33 (2009-03-12)
Despite important advances made in the last century, infectious diseases caused by pathogenic microrganisms are still a major threat to human health. This is worsened by the occurrence of new forms of bacterial resistance against antibiotics, that are the main
Cadi Davies et al.
Frontiers in cellular and infection microbiology, 9, 177-177 (2019-06-14)
Campylobacter jejuni outer membrane vesicles (OMVs) contain numerous virulence-associated proteins including the cytolethal distending toxin and three serine proteases. As C. jejuni lacks the classical virulence-associated secretion systems of other enteric pathogens that deliver effectors directly into target cells, OMVs
Aloka B Bandara et al.
PloS one, 6(4), e19003-e19003 (2011-05-06)
Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been postulated to be present around
Leticia Martínez-Lapuente et al.
Food research international (Ottawa, Ont.), 96, 235-243 (2017-05-22)
The effect of egg albumin fining, progressive clarification and cross-flow microfiltration on the polysaccharide and proanthocyanidin composition of four red varietal wines was studied in this work. Discriminant analyses were applied to achieve a possible differentiation of the wines according
Chiguang Feng et al.
PloS one, 7(4), e32359-e32359 (2012-04-13)
We previously reported that neuraminidase (NA) pretreatment of human PBMCs markedly increased their cytokine response to lipopolysaccharide (LPS). To study the mechanisms by which this occurs, we transfected HEK293T cells with plasmids encoding TLR4, CD14, and MD2 (three components of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service