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Key Documents

G5627

Sigma-Aldrich

Guaiacol glyceryl ether

≥98% (GC)

Synonym(s):

3-(o-Methoxyphenoxy)-1,2-propanediol, Glycerol guaiacolate, Guaifenesin

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About This Item

Empirical Formula (Hill Notation):
C10H14O4
CAS Number:
Molecular Weight:
198.22
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98% (GC)

SMILES string

COc1ccccc1OCC(O)CO

InChI

1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3

InChI key

HSRJKNPTNIJEKV-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Natividad Isabel Navarro Pacheco et al.
Nanomaterials (Basel, Switzerland), 11(1) (2021-01-23)
Titanium dioxide nanoparticles (TiO2 NPs) are manufactured worldwide. Once they arrive in the soil environment, they can endanger living organisms. Hence, monitoring and assessing the effects of these nanoparticles is required. We focus on the Eisenia andrei earthworm immune cells
Robert J Brosnan et al.
American journal of veterinary research, 72(12), 1569-1575 (2011-12-01)
To evaluate whether guaifenesin can prevent adverse anesthetic induction events caused by propofol and whether a guaifenesin-propofol induction combination has brief cardiovascular effects commensurate with rapid drug washout. 8 healthy adult horses. Guaifenesin was administered IV for 3 minutes followed
Nouruddin Wageih Ali et al.
Acta pharmaceutica (Zagreb, Croatia), 62(2), 191-200 (2012-07-04)
Accurate and sensitive methods were developed for simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium in their binary mixtures, and in the presence of a methocarbamol related substance (guaifenesin) using mean centering of the ratio spectra method. The results
Monzure-Khoda Kazi et al.
Journal of chromatography. A, 1231, 22-30 (2012-03-01)
This work addresses optimization of an improved single-column chromatographic (ISCC) process for the separation of guaifenesin enantiomers. Conventional feed injection and fraction collection systems have been replaced with customized components facilitating simultaneous separation and online monitoring with the ultimate objective
Mallinath B Hadimani et al.
Journal of medicinal chemistry, 56(12), 5071-5078 (2013-06-14)
In diabetic patients, an early index of peripheral neuropathy is the slowing of conduction velocity in large myelinated neurons and a lack of understanding of the basic pathogenic mechanisms hindered therapeutics development. Racemic (R/S)-guaifenesin (1) was identified as a potent

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