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Key Documents

A65182

Sigma-Aldrich

2-Amino-2-methyl-1-propanol

~5% Water, technical grade, 95%

Synonym(s):

β-Aminoisobutyl alcohol, AMP

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About This Item

Linear Formula:
(CH3)2C(NH2)CH2OH
CAS Number:
Molecular Weight:
89.14
Beilstein:
505979
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

Quality Level

vapor density

3 (vs air)

vapor pressure

<1 mmHg ( 25 °C)

Assay

95%

form

liquid

impurities

≤5% 2-(Methylamino)-2-methyl-1-propanol
~5% Water

refractive index

n20/D 1.4455 (lit.)

useful pH range

9.0-10.5

pKa (25 °C)

9.7

bp

165 °C (lit.)

mp

24-28 °C (lit.)

density

0.934 g/mL at 25 °C (lit.)

SMILES string

CC(C)(N)CO

InChI

1S/C4H11NO/c1-4(2,5)3-6/h6H,3,5H2,1-2H3

InChI key

CBTVGIZVANVGBH-UHFFFAOYSA-N

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Application

Used in an efficient synthesis of 2-oxazolidinones via carbonylation with CO in the presence of salen-cobalt catalysts.
Used to derivatize carboxylic acids for GC analysis and to synthesize 2-oxazolines for further transformations.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

154.4 °F - closed cup

Flash Point(C)

68 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Journal of Chromatography A, 673, 101-101 (1994)
Journal of the American Chemical Society, 114, 1010-1010 (1992)
Erik C B Johnson et al.
Tetrahedron letters, 48(10), 1795-1799 (2007-03-05)
Modification of a peptide-(α)thioester with a sequence of six arginines on the thioester leaving group can render soluble all peptides derived from a polytopic integral membrane protein. This strategy greatly simplifies the synthesis of peptide-(α)thioester building blocks for the total
Tetrahedron, 49, 9353-9353 (1993)
M Lamberto et al.
Analytical biochemistry, 230(2), 224-228 (1995-09-20)
The effect of derivatization with 2-amino-2-methyl-propanol on trans-3-hexadecenoic acid was investigated as part of the identification of the trans-3-hexadecenoic acid in two Nova Scotian seaweeds. After the extraction of the total fatty acids and their methylation, the monoenoic trans fraction

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