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A54059

Sigma-Aldrich

2-(2-Aminoethoxy)ethanol

98%

Synonym(s):

Diethylene glycolamine

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About This Item

Linear Formula:
NH2CH2CH2OCH2CH2OH
CAS Number:
Molecular Weight:
105.14
Beilstein:
906728
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

liquid

bp

218-224 °C (lit.)

density

1.048 g/mL at 25 °C (lit.)

SMILES string

NCCOCCO

InChI

1S/C4H11NO2/c5-1-3-7-4-2-6/h6H,1-5H2

InChI key

GIAFURWZWWWBQT-UHFFFAOYSA-N

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Application

2-(2-Aminoethoxy)ethanol is commonly used as a spacer/linker in the synthesis of bioconjugate materials for applications such as drug delivery and protein labeling. It is also employed as a receptor chain in the preparation of carboxamidoquinoline based water-soluble, ratiometric fluorescent zinc sensor.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

260.6 °F

Flash Point(C)

127 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Los, Georgyi V et al.
ACS Chemical Biology, 3(6), 373-382 (2008)
Cao-An Vu et al.
ACS omega, 4(12), 14765-14771 (2019-09-26)
Silicon nanowire field-effect transistors (SiNW-FETs) have been demonstrated as a highly sensitive platform for label-free detection of a variety of biological and chemical entities. However, detecting signal from immunoassays by nano-FETs is severely hindered by the distribution of different charged
C Tournaire-Arellano et al.
Carbohydrate research, 314(1-2), 47-63 (1999-05-07)
Ureido and thioureido derivatives of 2-acetamido-2-deoxy-beta-D-glucose, 1-amino-1-deoxy-D-glucitol and 2-(2-aminoethoxy)ethanol were prepared as N-acetyl-beta-D-hexosaminidase (NAHase) inhibitors and were evaluated on Trichomonas vaginalis NAHase. Although none showed complete inhibition of the enzyme at 100 microM, 1-amino-1-deoxy-D-glucitol derivatives acted as competitive inhibitors of
B Combourieu et al.
Applied and environmental microbiology, 64(1), 153-158 (1998-01-22)
Resting Mycobacterium aurum MO1 cells were incubated with morpholine, a waste from the chemical industry. The kinetics of biodegradation was monitored by using in situ nuclear magnetic resonance (NMR). The incubation medium was directly analyzed by 1H NMR. This technique
Yuliya V Sherstyuk et al.
Molecular diversity, 21(1), 101-113 (2016-09-30)
A versatile strategy for the synthesis of [Formula: see text] mimetics was developed, involving an efficient pyrophosphate linkage formation in key conjugates containing a functional amino group which acts as useful reactive anchor for further derivatization. These [Formula: see text]

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