935468

Aldehyde functionalized hyaluronic acid

Degree of functionalization ~40%

• Synonym(s): HA aldehyde, HA-A, Hyaluronic acid A. Oxidized Hyaluronic acid
• Linear Formula: (C₁₄H₂₀NNaO₁₁)_n(C₁₄H₁₈NNaO₁₁)_m
• UNSPSC Code: 12352201
• NACRES: NA.28

Properties

• Quality Level: 100
• form: powder or chunks ( or fibers)
• color: white to off-white
• storage temp.: −20°C

Description

General description

Hyaluronic acid (HA) is an important component of the natural extracellular matrix which plays a vital role in various cellular and tissue functions. It represents some unique properties such as excellent gel-forming properties and chemical modification ability through hydroxyl and carboxyl groups that make them useful for tissue engineering applications. Aldehyde functionalized hyaluronic acid, or partially oxidized hyaluronic acid, contains two aldehyde groups in the repeating unit of HA. The dialdehyde groups are capable of reductive coupling with primary amines, providing a platform for a wide range of chemical modifications for a variety of applications.

Application

HA is increasingly used for a many biomedical applications because it promotes cell migration, angiogenesis, cell viability, and proliferation. Aldehyde functionalized HA can be used to develop hydrogels for tissue engineering, regenerative medicing, bioprinting, and drug delivery applications.

Features and Benefits

• Coupling capabilities with primary amines
• Biocompatible functionalized natural polymer
• Promotes a variety of cellular and tissue functions

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable