926175
Glycol Chitosan Methacrylate
Degree of methacrylation ∼45%
Synonym(s):
Chitosan hydrogel, Crosslinkble chitosan, Glycol chitosan, Methacrylated glycol chitosan
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About This Item
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Quality Level
form
powder
color
white to light yellow, light brown
suitability
conforms to structure for NMR
storage temp.
2-8°C
Application
Glycol chitosan is soluble at neutral pH and possesses potentially useful biological properties such as good biocompatibility accelerate wound healing, and antimicrobial properties, and it is less toxic and provide to stimulates chondrocyte growth at low concentrations. Methacrylated glycol chitosan is photo- and thermally cross-linkable and is used as a precursor for the preparation of hydrogels used in biomedical applications including drug delivery, tissue engineering, and 3D bioprinting.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
Acta Pharmaceutica Sinica. B, Volume 2, Issue 5, 439-449 (2012)
Biomacromolecules, 8(12), 3758-3766 (2007-11-23)
Glycol chitosan is a derivative of chitosan that is soluble at neutral pH and possesses potentially useful biological properties. With the goal of obtaining biocompatible hydrogels for use as tissue engineering scaffolds or drug delivery depots, glycol chitosan was converted
Biomaterials, 16(16), 1211-1216 (1995-11-01)
Chitosan was selectively N-acylated with various carboxylic anhydrides, e.g., acetic, propionic, n-butyric, n-valeric and n-hexanoic anhydrides, in the presence of methanol. The degree of N-acylation of about 20-50% was obtainable without occurrence of gelation by using carboxylic anhydrides of 0.3-1.2
Carbohydrate polymers, 245, 116496-116496 (2020-07-29)
Hydrogel systems that show self-healing ability after mechanical damage are receiving increasing attention. However, self-healing hydrogels suitable for biomedical applications are limited owing to complex preparation methods. Furthermore, few studies have demonstrated the self-healing property of ferrogels. In this study
Evaluation of the Properties of Soluble Chitosan and Chitosan Microspheres
International Journal of Pharmaceutics, 148 (2), 231-240 (1997)
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