922684
N-Methyl-O-nosylhydroxylammonium triflate
Synonym(s):
NsONH2Me·OTf
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C8H9F3N2O8S2
CAS Number:
Molecular Weight:
382.29
UNSPSC Code:
12352101
Recommended Products
form
powder
Quality Level
mp
79.8-109.2 °C (Decomp.)
functional group
amine
fluoro
nitro
sulfonic acid
triflate
storage temp.
−20°C
Application
N-Methyl-O-nosylhydroxylammonium triflate is a reagent used in iron catalyzed synthesis of N-methylamines from simple arenes. This reagent can be used to form various aryl amines without the use of precious metal catalysts, harsh conditions or complex multi-step syntheses, and represents a more robust alternative to other coupling methods of forming sp2 C-N bonds.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Org. Perox. C - Skin Irrit. 2
Storage Class Code
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Synthesis of N-Alkyl Anilines from Arenes via Iron-Promoted Aromatic C-H Amination.
Falk, et al.
Organic Letters, 23, 1422-1426 (2021)
Eric Falk et al.
Organic letters, 23(4), 1422-1426 (2021-02-06)
We report both an intermolecular C-H amination of arenes to access N-methylanilines and an intramolecular variant for the synthesis of tetrahydroquinolines. A newly developed, highly electrophilic aminating reagent was key for the direct synthesis of unprotected N-methylanilines from simple arenes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service