855286
5-Aminouracil
98%
Synonym(s):
5-Amino-2,4-dihydroxypyrimidine, 5-Amino-2,4-pyrimidinediol
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About This Item
Empirical Formula (Hill Notation):
C4H5N3O2
CAS Number:
Molecular Weight:
127.10
Beilstein:
127250
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder
mp
>300 °C (lit.)
SMILES string
NC1=CNC(=O)NC1=O
InChI
1S/C4H5N3O2/c5-2-1-6-4(9)7-3(2)8/h1H,5H2,(H2,6,7,8,9)
InChI key
BISHACNKZIBDFM-UHFFFAOYSA-N
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Signal Word
Warning
Hazard Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Paulina Spisz et al.
International journal of molecular sciences, 21(17) (2020-09-05)
Hypoxia-a hallmark of solid tumors-dramatically impairs radiotherapy, one of the most common anticancer modalities. The adverse effect of the low-oxygen state can be eliminated by the concomitant use of a hypoxic cell radiosensitizer. In the present paper, we show that
K K Upadhyay et al.
Talanta, 82(2), 845-849 (2010-07-07)
An interference-free naked-eye recognition of Al(3+) at its micromolar level has been done in 5% aqueous DMSO solution employing a Schiff base 5-[(2-hydroxy-5-nitro-benzylidene)-amino]-1H-pyrimidine-2,4-dione (receptor 1) which is an intramolecular charge transfer (ICT) probe. The pyrimidine and nitrophenyl groups serve as
A Del Campo et al.
Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 29(2), 169-176 (2005-09-29)
This work evaluated the qualitative and quantitative cellular changes induced by treatment with 5-aminouracil (5-AU) and a combination of 5-AU and caffeine in plant cells in relation to DNA damage, repaired damage, and residual damage. As biological material, Allium cepa
M H Navarrete et al.
Experimental cell research, 148(2), 273-280 (1983-10-15)
Meristematic cells from Allium cepa L roots can attain a steady-state of growth at both 15 and 25 degrees C in the presence of drugs, hydroxyurea and 5-amino-uracil, which reduce the rate of DNA synthesis. These drugs, at used concentrations
K K Upadhyay et al.
Organic & biomolecular chemistry, 8(21), 4892-4897 (2010-09-08)
A new fluorescent probe (5-[(4-diethylamino-2-hydroxy-benzylidene)-amino]-1H-pyrimidine-2, 4-dione) (Receptor 1) has been synthesized by the Schiff base condensation of 5-aminouracil with 4-(diethylamino)salicylaldehyde. The receptor 1 exhibits high selectively for Al(3+) in DMSO as well as in aqueous solution even in the presence
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