Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

717142

Sigma-Aldrich

Poly(ethylene glycol) dithiol

average Mn 1,000, thiol

Synonym(s):

Polyethylene glycol, PEG dithiol

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
HSCH2CH2(OCH2CH2)nSH
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) dithiol, average Mn 1,000

form

solid

Quality Level

100

mol wt

average Mn 1,000

reaction suitability

reagent type: cross-linking reagent
reactivity: thiol reactive

mp

29-33 °C

Ω-end

thiol

α-end

thiol

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Thiol functionalized nanoparticles may be used in mucoadhesive drug delivery, synthesis of dithiol terminated amphiphilic diblock copolymer, Bidentate dithiol-poly(ethylene glycol)-poly(d,l-lactide) (SH2-PEG-PDLLA). Gold nanoparticles may be easily functionalized with PEG dithiols by simple ligand exchange.

Other Notes

Molecular weight: Mn 900-1,100

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCW4873
MKCR7598
MKCQ0755
MKCH8048
MKCG7818

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jian Yang et al.
Biomacromolecules, 15(4), 1346-1354 (2014-03-13)
Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene
Nadeau J
Introduction to Experimental Biophysics: Biological Methods for Physical Scientists null
Qiang Wei et al.
ACS biomaterials science & engineering, 6(8), 4687-4701 (2021-01-19)
Hydrogels have been widely explored for the delivery of cells in a variety of regenerative medicine applications due to their ability to mimic both the biochemical and physical cues of cell microniches. For bone regeneration, in particular, stiff hydrogels mimicking

Articles

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service