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541397

Sigma-Aldrich

10-Bromodecanoic acid

95%

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About This Item

Linear Formula:
Br(CH2)9CO2H
CAS Number:
Molecular Weight:
251.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

95%

reaction suitability

reagent type: linker

mp

38-41 °C (lit.)

functional group

bromo
carboxylic acid

SMILES string

OC(CCCCCCCCCBr)=O

InChI

1S/C10H19BrO2/c11-9-7-5-3-1-2-4-6-8-10(12)13/h1-9H2,(H,12,13)

InChI key

PGVRSPIEZYGOAD-UHFFFAOYSA-N

General description

10-Bromodecanoic acid can be prepared from 10-bromodecanol via oxidation.

Application

10-Bromodecanoic acid may be employed as an alkylcarboxylate chain source in the preparation of alkylcarboxylate-grafted polyethylenimine. It may also be used in the synthesis of :
  • 10-(methylsulfinyl)decanoic acid
  • 10-cyanodecanoic acid
  • (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)-decyl)triphenylphosphonium bromide
  • 11-thiastearic acid

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M D Rahman et al.
Journal of medicinal chemistry, 31(8), 1656-1659 (1988-08-01)
A variety of analogues of stearic acid in which one of the methylene groups was replaced by a sulfur atom were examined as inhibitors of growth and fatty acid biosynthesis in the trypanosomatid protozoan Crithidia fasciculata. The 8-, 9-, 10-
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Poor water solubility of hydrophobic drugs is one of the major problems in pharmaceutical sciences. Herein, in order to address the poor solubility of crocetin, the 30% of primary amines of PAMAM G4 and PPI G4 were alkylated and evaluated
Reza K Oskuee et al.
The journal of gene medicine, 11(10), 921-932 (2009-07-28)
Various strategies have been examined to improve both transfection efficiency and cytotoxicity of polyethylenimine (PEI), a widely used polycationic nonviral gene vector. In the present study, we sought to improve PEI transfection efficiency by combining the osmotic burst mechanism for
Sara Ayatollahi et al.
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RNAi-based gene therapy has been recently considered as a promising approach against cancer. Targeted delivery of drug, gene or therapeutic RNAi-based systems to tumor cells is one of the important issues in order to reduce side effects on normal cells.
Anodic Syntheses Involving ω-Monohalocarboxylic Acids1.
Pattison FLM, et al.
Journal of the American Chemical Society, 78(10), 2255-2259 (1956)

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