473936
N-Methylformamide
99%
Synonym(s):
N-Formylmethylamine
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About This Item
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Quality Level
Assay
99%
refractive index
n20/D 1.432 (lit.)
bp
198-199 °C (lit.)
mp
−4 °C (lit.)
density
1.011 g/mL at 25 °C (lit.)
functional group
amide
SMILES string
[H]C(=O)NC
InChI
1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)
InChI key
ATHHXGZTWNVVOU-UHFFFAOYSA-N
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General description
N-Methylformamide (NMF), a formamide derivative, is widely employed as an organic solvent. NMF molecule contains C=O and N-H groups, so it can act as a proton donor and acceptor. Its antitumor activities in mice have been assessed. Optical-heterodyne-detected optical Kerr effect (OHD-OKE) spectroscopic evaluation of NMF has been reported. Due to its important physical properties such as high dielectric constant, high solubility, low conductivity and amphiprotic nature, it is suitable for use as a separation medium in capillary electrophoresis studies.
Application
N-Methylformamide may be employed in the preparation of the following:
- Li2S-P2S5 solid electrolytes (SE)
- interlayer-condensed materials of protonated layered silicate (magadiite)
- Li3PS4 solid electrolyte
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
Flash Point(F)
231.8 °F - closed cup
Flash Point(C)
111 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Liquid-phase synthesis of a Li3PS4 solid electrolyte using N-methylformamide for all-solid-state lithium batteries.
Journal of Material Chemistry A, 2(14), 5095-5099 (2014)
Preparation of Li2S-P2S5 solid electrolyte from N-methylformamide solution and application for all-solid-state lithium battery.
Journal of Power Sources, 248, 939-942 (2014)
Femtosecond dynamics of hydrogen-bonding solvents. Formamide and N-methylformamide in acetonitrile, DMF, and water.
J. Chem. Phys. , 99(1), 113-125 (1993)
Interlayer condensation of protonated layered silicate magadiite through refluxing in N-methylformamide.
Bulletin of the Chemical Society of Japan, 88(9), 1241-1249 (2015)
The journal of physical chemistry. B, 113(16), 5622-5632 (2009-03-31)
N-methylformamide (NMF), the simplest model for peptides, exhibits hyperplectic (both simple and complex) behavior as revealed by thin film infrared spectroscopy on planar AgX [AgCl:AgBr] fiber. IR spectra (0.1 s scans) of 10 microg NMF/dichloromethane(DCM) under N(2) flow first show
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