413364

3-(Triethoxysilyl)propyl isocyanate

95%

• Synonym(s): Triethoxy(3-isocyanatopropyl)silane, (3-Isocyanatopropyl)triethoxysilane
• Linear Formula: (C₂H₅O)₃Si(CH₂)₃NCO
• CAS Number: 24801-88-5
• Molecular Weight: 247.36
• Beilstein: 4404652
• EC Number: 246-467-6
• MDL number: MFCD00051459
• UNSPSC Code: 12352103
• PubChem Substance ID: 24865861
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 95%
• form: liquid
• refractive index: n20/D 1.42 (lit.)
• bp: 283 °C (lit.)
• density: 0.999 g/mL at 25 °C (lit.)
• functional group: amine; isocyanate
• SMILES string: CCO[Si](CCCN=C=O)(OCC)OCC
• InChI: 1S/C10H21NO4Si/c1-4-13-16(14-5-2,15-6-3)9-7-8-11-10-12/h4-9H2,1-3H3
• InChI key: FRGPKMWIYVTFIQ-UHFFFAOYSA-N

Description

Application

3-(Triethoxysilyl)propyl isocyanate can be used:

• As a bifunctional reagent (isocyanate and ethoxysilyl groups) for the immobilization of cellulose derivatives onto silica matrix to generate bonded type of chiral stationary phases (CSPs).
• To convert 5-amino-1,10-phenanthroline into 5-(N,N-bis-3-(triethoxysilyl)propyl)-ureyl-1,10-phenanthroline, a hydrolysable sol–gel precursor.
• To synthesize ruthenium bipyridyl tethered porous organosilica(Ru-POS) for organo-photocatalysis.
• To synthesize nanoparticle-supported oxime palladacycle catalyst for Suzuki-Miyaura cross-coupling reaction.

3-(triethoxysilyl)propyl isocyanate (TEPI) was used as a spacer reagent to prepare cellulose based chiral stationary phases (CSPs). TEPI may be used to modify 2-hydroxynicotinic acid to prepare luminescent hybrid materials.2 Luminescent inorganic-organic hybrid materials were prepared by grafting the isocynate with the ortho aminobenzoic acid derivative. TEPI may also be used to prepare 5-(N,N-bis-3-(triethoxysilyl)propyl)ureyl-1,10- phenanthroline (phen-Si).

Safety Information

• Pictograms: GHS06,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H302 + H312,H314,H317,H330,H334
• Precautionary Statements: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): 223.7 °F - closed cup
• Flash Point(C): 106.5 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves