301507
2-Mercapto-1-methylimidazole
≥99%
Synonym(s):
Methimazole, 1-Methyl-2-imidazolethiol, 2-Mercapto-1-methylimidazole
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About This Item
Empirical Formula (Hill Notation):
C4H6N2S
CAS Number:
Molecular Weight:
114.17
Beilstein:
108646
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22
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Assay
≥99%
mp
144-147 °C (lit.)
SMILES string
CN1C=CNC1=S
InChI
1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
InChI key
PMRYVIKBURPHAH-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544) , TPO(7173)
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General description
Sensitive detection of 2-mercapto-1-methylimidazole by Au-Ag-Au double shell nanoparticles-based localized surface plasmon resonance and surface-enhanced Raman scattering biosensor was reported.
Application
2-Mercapto-1-methylimidazole was employed as hydrophobic charge-induction chromatography ligand for antibody purification. It was also used in preparation of nitrile functionalized methimazole-based room temperature ionic liquids.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hui-Li Lu et al.
Journal of chromatography. A, 1278, 61-68 (2013-01-23)
Hydrophobic charge-induction chromatography (HCIC) is a novel technology for antibody purification. The ligand densities and pore properties of HCIC resins have significant effects on the separation behavior of protein, however, the understandings are quite limited. In the present work, new
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Amal I Siriwardana et al.
The Journal of organic chemistry, 75(24), 8376-8382 (2010-11-18)
The alkylation reaction of 2-mercapto-1-methylimidazole 1b with 2-chloroacetonitrile and 2-chloropropionitrile produced S-alkyl methimazole chlorides 2a and 2b which were subjected to anion metathesis with lithium bis(trifluoromethanesulfonyl)amide, LiNTf(2), to afford nitrile functionalized methimazole-based room temperature ionic liquids 3a and 3b in
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