268542
Hydroxypropyl methacrylate
Mixture of hydroxypropyl and hydroxyisopropyl methacrylates, 97%, contains 180-220 ppm monomethyl ether hydroquinone as inhibitor
Synonym(s):
HPMA
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About This Item
Recommended Products
vapor density
>1 (vs air)
Quality Level
vapor pressure
0.05 mmHg ( 20 °C)
Assay
97%
form
liquid
contains
180-220 ppm monomethyl ether hydroquinone as inhibitor
refractive index
n20/D 1.447 (lit.)
bp
57 °C/0.5 mmHg (lit.)
density
1.066 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
CC(=C)C(=O)OCCCO
InChI
1S/C7H12O3/c1-5(2)7(9)10-6(3)4-8/h6,8H,1,4H2,2-3H3
InChI key
ZMARGGQEAJXRFP-UHFFFAOYSA-N
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Application
- Synthesis of poly hydroxypropyl methacrylate cryogel incorporated with Zn/Ce substituted hydroxyapatite nanoparticles for rejuvenation of femoral fracture: This study explores the synthesis of a cryogel incorporating hydroxypropyl methacrylate and Zn/Ce substituted hydroxyapatite nanoparticles, aimed at bone fracture healing (H Zhou, H Jiao, J Xu, Y Liu, S Wei, 2019).
- Poly(Hydroxypropyl methacrylate-co-glycidyl methacrylate): Facile synthesis of well-defined hydrophobic gels containing hydroxy-functional methacrylates: This article presents the synthesis of hydrophobic gels using hydroxypropyl methacrylate and glycidyl methacrylate, useful in various material applications (N Orakdogen, B Sanay, 2017).
- Initiated chemical vapor deposition of poly(Hydroxypropyl methacrylate) thin films: The study covers the chemical vapor deposition process for creating thin films of poly(hydroxypropyl methacrylate) on membranes, enhancing their functional properties (E Sevgili, M Karaman, 2019).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
203.0 °F - closed cup
Flash Point(C)
95 °C - closed cup
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Annette Kelsch et al.
Biomacromolecules, 13(12), 4179-4187 (2012-11-28)
In this work we describe the application of amphiphilic N-(2-hydroxypropyl)methacrylamide (HPMA)-based copolymers as polymeric surfactants in miniemulsion techniques. HPMA-based copolymers with different ratios of HPMA (hydrophilic) to laurylmethacrylate (LMA; hydrophobic) units were synthesized by RAFT polymerization and postpolymerization modification. The
Russell N Johnson et al.
Biomacromolecules, 13(3), 727-735 (2012-02-01)
High-molecular-weight, branched N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers were synthesized and conjugated with Fab' fragments of the anti-CD20 antibody, 1F5. This produced multivalent conjugates with varying valency (amount of Fab' per macromolecule) targeted to the B-cell antigen CD20. The apoptotic activity of the
Qingyu Xiang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(2), 379-386 (2011-11-22)
In several groups of malignant tumors including head and neck tumors, a protein named Hsp47/CBP2 leaked from the cell was expressed on the tumor cell surface. Several synthetic peptides have been identified as effective ligands for binding to Hsp47/CBP2. This
Tomáš Etrych et al.
Journal of controlled release : official journal of the Controlled Release Society, 154(3), 241-248 (2011-06-28)
Herein, new biodegradable star polymer-doxorubicin conjugates designed for passive tumor targeting were investigated, and their synthesis, physico-chemical characterization, drug release, biodegradation, biodistribution and in vivo anti-tumor efficacy are described. In the conjugates, the core formed by poly(amidoamine) (PAMAM) dendrimers was
Adam J Gormley et al.
Journal of controlled release : official journal of the Controlled Release Society, 166(2), 130-138 (2012-12-25)
Effective drug delivery to tumors requires both transport through the vasculature and tumor interstitium. Previously, it was shown that gold nanorod (GNR) mediated plasmonic photothermal therapy (PPTT) is capable of increasing the overall accumulation of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers in prostate
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