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26564

Sigma-Aldrich

Chlorotripyrrolidinophosphonium hexafluorophosphate

≥98.0% (AT)

Synonym(s):

PyCloP

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About This Item

Linear Formula:
C12H24ClN3P · PF6
CAS Number:
Molecular Weight:
421.73
Beilstein:
6842341
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98.0% (AT)

form

solid

reaction suitability

reaction type: Coupling Reactions

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

F[P-](F)(F)(F)(F)F.Cl[P+](N1CCCC1)(N2CCCC2)N3CCCC3

InChI

1S/C12H24ClN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1

InChI key

BSCYRXJVGSZNKX-UHFFFAOYSA-N

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Application

Reagent for:
Peptide coupling reactions and synthesis of coupling reagents
Sequence selective peptide recognition
Synthesis of condensing reagents
Synthesis of heterocyclic β-sheet ligands

Other Notes

Crystalline reagent for peptide coupling of N-alkylated N-Fmoc and N-Z amino acids in high yield and without racemization.

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J. Coste et al.
The Journal of Organic Chemistry, 59, 2437-2437 (1994)

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