261971

Tricyclohexylphosphine

• Synonym(s): PCy₃, P(Cy)₃
• Linear Formula: (C₆H₁₁)₃P
• CAS Number: 2622-14-2
• Molecular Weight: 280.43
• EC Number: 220-069-2
• MDL number: MFCD00003853
• UNSPSC Code: 12350000
• PubChem Substance ID: 24855848
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• reaction suitability: reaction type: Cross Couplings; reagent type: ligand; reaction type: Heck Reaction; reagent type: ligand; reaction type: Hiyama Coupling; reagent type: ligand; reaction type: Sonogashira Coupling; reagent type: ligand; reaction type: Suzuki-Miyaura Coupling
• mp: 81-83 °C (lit.)
• functional group: phosphine
• SMILES string: C1CCC(CC1)P(C2CCCCC2)C3CCCCC3
• InChI: 1S/C18H33P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h16-18H,1-15H2
• InChI key: WLPUWLXVBWGYMZ-UHFFFAOYSA-N

Description

Application

Ligand used in the Pd-catalyzed coupling of malononitrile with aryl halides. Bulky phosphine ligand used with a Pd(0)-triolefinic macrocycle catalyst for Suzuki coupling of aryl bromides and chlorides.

This ligand is applied with Ni as a key intermediate in the formation of cylcopentane compounds.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves