237647
L−(+)-α-Phenylglycine
99%
Synonym(s):
(S)-(+)-2-Phenylglycine, S-(+)-α-Aminophenylacetic acid, L-2-Phenylglycine
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About This Item
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Quality Level
Assay
99%
form
powder
optical activity
[α]20/D +155°, c = 1 in 1 M HCl
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
N[C@H](C(O)=O)c1ccccc1
InChI
1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m0/s1
InChI key
ZGUNAGUHMKGQNY-ZETCQYMHSA-N
Application
Chiral starting material.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The Journal of chemical physics, 128(18), 184313-184313 (2008-06-06)
We investigated the conformational structures of L-phenylglycine in the gas phase by photoionization and double resonance spectroscopy techniques as well as high-level ab initio calculations. The UV-UV and IR-UV double resonance spectroscopy suggested that there exists only one conformer that
Biochimica et biophysica acta, 1770(11), 1585-1592 (2007-10-06)
Following induction with D-phenylglycine both d-phenylglycine aminotransferase activity and benzoylformate decarboxylase activity were observed in cultures of Pseudomonas stutzeri ST-201. Induction with benzoylformate, on the other hand, induced only benzoylformate decarboxylase activity. Purification of the benzoylformate decarboxylase, followed by N-terminal
The Journal of organic chemistry, 75(8), 2645-2650 (2010-03-23)
A range of alpha-amino esters has been synthesized in good to high yields using a straightforward three-component reaction among preformed or in situ generated aromatic or benzylic organozinc reagents, primary or secondary amines, and ethyl glyoxylate. The procedure, which is
Pain, 125(1-2), 136-142 (2006-06-20)
Gabapentin and pregabalin have been demonstrated, both in animal pain models and clinically, to be effective analgesics particularly for the treatment of neuropathic pain. The precise mechanism of action for these two drugs is unknown, but they are generally believed
Bioorganic & medicinal chemistry, 15(3), 1448-1474 (2006-11-23)
Molecular modeling and inhibitory potencies of tetrapeptide protease inhibitors of HCV NS3 proposed phenylglycine as a new promising P2 residue. The results suggest that phenylglycine might be capable of interacting with the NS3 (protease-helicase/NTPase) in ways not possible for the
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