224464

(1S,2R,5S)-(+)-Menthol

99%

• Synonym(s): (+)-Menthol, (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanol
• Empirical Formula (Hill Notation): C₁₀H₂₀O
• CAS Number: 15356-60-2
• Molecular Weight: 156.27
• Beilstein: 1902292
• EC Number: 239-387-8
• MDL number: MFCD00062983
• UNSPSC Code: 12352212
• PubChem Substance ID: 24853440
• NACRES: NA.22

Properties

• vapor pressure: 0.8 mmHg ( 20 °C)
• Assay: 99%
• form: solid
• optical activity: [α]23/D +48°, c = 10 in ethanol
• optical purity: ee: 96% (GLC)
• bp: 103-104 °C/9 mmHg (lit.)
• mp: 43-44 °C (lit.)
• functional group: hydroxyl
• SMILES string: CC(C)[C@H]1CC[C@H](C)C[C@@H]1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m0/s1
• InChI key: NOOLISFMXDJSKH-AEJSXWLSSA-N
• Gene Information: human ... UGT1A4(54657)

Description

General description

(1S,2R,5S)-(+)-menthol is a chiral secondary alcohol. Its alcohol group can be protected as 2-tetrahydrofuranyl ether by reacting with bromotrichloromethane and tetrahydrofuran.

Application

(1S,2R,5S)-(+)-menthol can undergo acylation with acid anhydrides in the presence of trimethylsilyl trifluoromethanesulfonate to form the corresponding acylated products.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H315,H318,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 213.8 °F - closed cup
• Flash Point(C): 101 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves