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Key Documents

223298

Sigma-Aldrich

N-(Trimethylsilyl)acetamide

95%

Synonym(s):

TMS acetamide

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About This Item

Linear Formula:
CH3CONHSi(CH3)3
CAS Number:
Molecular Weight:
131.25
Beilstein:
741928
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

95%

form

solid

bp

84 °C/18 mmHg (lit.)

mp

46-49 °C (lit.)

SMILES string

CC(=O)N[Si](C)(C)C

InChI

1S/C5H13NOSi/c1-5(7)6-8(2,3)4/h1-4H3,(H,6,7)

InChI key

LWFWUJCJKPUZLV-UHFFFAOYSA-N

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General description

The efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

158.0 °F

Flash Point(C)

70 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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New allyl group acceptors for palladium catalyzed removal of allylic protections and transacylation of allyl carbamates.
Tetrahedron Letters, 36(32), 5741-5744 (1995)

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